(Q35224798)

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A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 August 2017

A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C). (English)

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Europe PubMed Central

PubMed publication ID

7 August 2017

toll-like receptor

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Parkinson's disease

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based on heuristic

inferred from title

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815475%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Penelope J. Hallett

10

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7 June 2020

11

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7 June 2020

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Emily M Rocha

2

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7 June 2020

Thomas Rooney

3

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7 June 2020

Pascal Barneoud

4

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7 June 2020

Jesse R McLean

5

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7 June 2020

Jonathan Beagan

6

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7 June 2020

Teresia Osborn

7

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7 June 2020

Madeleine Coimbra

8

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7 June 2020

Yongyi Luo

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7 June 2020

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27 March 2015

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7 August 2017

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7 June 2020

10

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7 June 2020

3

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7 June 2020

e0121072

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815475%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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Creative Commons Attribution 4.0 International

27 March 2015

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April 2022 Public Data File from Crossref

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Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats

1 reference

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13 July 2018

The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed

1 reference

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13 July 2018

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation

1 reference

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13 July 2018

NURR1 in Parkinson disease--from pathogenesis to therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Cellular and molecular mediators of neuroinflammation in the pathogenesis of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Maternal inflammation promotes fetal microglial activation and increased cholinergic expression in the fetal basal forebrain: role of interleukin-6.

1 reference

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13 July 2018

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice

1 reference

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The role of markers of inflammation in traumatic brain injury.

1 reference

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13 July 2018

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

The function and mechanisms of Nurr1 action in midbrain dopaminergic neurons, from development and maintenance to survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Viral and inflammatory triggers of neurodegenerative diseases

1 reference

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13 July 2018

The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Expressions and possible roles of GDNF receptors in the developing dopaminergic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Peripheral challenge with double-stranded RNA elicits global up-regulation of cytokine gene expression in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Parkin deficiency increases vulnerability to inflammation-related nigral degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

13 July 2018

Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

1 reference

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13 July 2018

Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376720

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Bdnf gene is a downstream target of Nurr1 transcription factor in rat midbrain neurons in vitro

1 reference

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Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: moderation by social stressors

1 reference

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Nurr1 in Parkinson's disease and related disorders

1 reference

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The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

1 reference

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Nurr1 mutational screen in Parkinson's disease

1 reference

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Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation

1 reference

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Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25815475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0121072

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815475%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2015PLoSO..1021072S

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815475%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815475%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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