(Q35228094)

English

Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions (English)

1 reference

Europe PubMed Central

7 August 2017

lipopolysaccharide

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toll-like receptor

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Harry Björkbacka

object named as

Harry Björkbacka

3

0 references

Douglas T Golenbock

4

object named as

Douglas T Golenbock

1 reference

Europe PubMed Central

7 August 2017

author name string

Jianmin Meng

1

1 reference

Europe PubMed Central

7 August 2017

Mei Gong

2

1 reference

Europe PubMed Central

7 August 2017

language of work or name

0 references

publication date

24 August 2011

1 reference

Europe PubMed Central

7 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

7 August 2017

187

1 reference

Europe PubMed Central

7 August 2017

3683-3693

1 reference

Europe PubMed Central

7 August 2017

7

1 reference

Europe PubMed Central

7 August 2017

Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis.

1 reference

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13 July 2018

MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVA.

1 reference

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13 July 2018

Localisation and trafficking of Toll-like receptors: an important mode of regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

LPS/TLR4 signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

1 reference

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13 July 2018

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

1 reference

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13 July 2018

Lipid A modification systems in gram-negative bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response

1 reference

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13 July 2018

Sepsis: still going strong

1 reference

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13 July 2018

TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Lipopolysaccharide heterogeneity: innate host responses to bacterial modification of lipid a structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Identifying biological themes within lists of genes with EASE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

TM4: a free, open-source system for microarray data management and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Innate immune recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Antimicrobial peptides of multicellular organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

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The Toll receptor family and microbial recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

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Innate immune recognition: mechanisms and pathways

1 reference

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13 July 2018

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

The chemical structure of bacterial endotoxin in relation to bioactivity

1 reference

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Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis

1 reference

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13 July 2018

Bacterial endotoxin: molecular relationships of structure to activity and function

1 reference

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13 July 2018

CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide

1 reference

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13 July 2018

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide

1 reference

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13 July 2018

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking.

1 reference

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Human phagocytes have multiple lipid A-binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

13 July 2018

Binding sites for endotoxins (lipopolysaccharides) on human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

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Septic shock: treatment

1 reference

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Immunization with the Haemophilus ducreyi hemoglobin receptor HgbA with adjuvant monophosphoryl lipid A protects swine from a homologous but not a heterologous challenge

1 reference

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The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

26 September 2018

Treatment with an anti-CD14 monoclonal antibody delays and inhibits lipopolysaccharide-induced gene expression in humans in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178671

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Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

1 reference

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Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21865549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of macrophage-mediated tumor cytotoxicity by a hamster monoclonal antibody with specificity for lipopolysaccharide receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865549

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21865549

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21865549

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1101397

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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