(Q35230306)

7 August 2017

title

Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism (English)

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7 August 2017

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4

Paul S Pagel

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7 August 2017

Weidong Gu

1

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7 August 2017

Franz Kehl

2

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7 August 2017

John G Krolikowski

3

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7 August 2017

David C Warltier

5

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7 August 2017

Judy R Kersten

6

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7 August 2017

language of work or name

English

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publication date

1 April 2008

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7 August 2017

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7 August 2017

volume

108

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7 August 2017

issue

4

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7 August 2017

page(s)

634-642

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Improved postoperative outcomes associated with preoperative statin therapy.

7 August 2017

cites work

1 reference

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Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited

27 July 2018

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KATP channels and myocardial preconditioning: an update

27 July 2018

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

27 July 2018

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The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide

27 July 2018

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Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease.

27 July 2018

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Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

27 July 2018

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Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

27 July 2018

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Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels.

27 July 2018

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Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

27 July 2018

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Determination of Experimental myocardial infarct size

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Role of ATP dependent potassium channels in myocardial ischaemia

27 July 2018

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Alterations of alpha-adrenergic modulations of coronary microvascular tone in dogs with heart failure

27 July 2018

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MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Early preconditioning prevents the loss of endothelial nitric oxide synthase and enhances its activity in the ischemic/reperfused rat heart

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Guiding principles for research involving animals and human beings.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Isoflurane-induced preconditioning is attenuated by diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Hyperglycemia prevents isoflurane-induced preconditioning against myocardial infarction

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Pretreatment with simvastatin attenuates myocardial dysfunction after ischemia and chronic reperfusion

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

The contribution of endothelial nitric oxide synthase to early ischaemic preconditioning: the lowering of the preconditioning threshold. An investigation in eNOS knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

HMG-CoA reductase inhibition protects the diabetic myocardium from ischemia-reperfusion injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Potentiation by nitric oxide of the ATP-sensitive K+ current induced by K+ channel openers in guinea-pig ventricular cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378683

Emerging mechanisms for secondary cardioprotective effects of statins

26 September 2018

1 reference

12 December 2020

Myocardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase

1 reference

12 December 2020

Oxidized low-density lipoproteins and microvascular responses to ischemia-reperfusion

1 reference

12 December 2020

Nitric oxide-induced cardioprotection in cultured rat ventricular myocytes

1 reference

12 December 2020

Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

Total and Regional Coronary Blood Flow Measured by Radioactive Microspheres in Conscious and Anesthetized Dogs

1 reference

12 December 2020

Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts

1 reference

12 December 2020

Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality

1 reference

12 December 2020

Acute hyperglycemia abolishes ischemic preconditioning in vivo

1 reference

12 December 2020

Nitric oxide: a trigger for classic preconditioning?

1 reference

12 December 2020

10.1097/ALN.0B013E3181672590

Identifiers

DOI

1 reference

7 August 2017

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7 August 2017

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