(Q35235740)

7 August 2017

title

Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency (English)

1 reference

7 August 2017

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1 reference

2

Raoul V Kuiper

1 reference

7 August 2017

Sebastiaan van Heesch

object named as

Sebastiaan van Heesch

4

0 references

Ruben van Boxtel

object named as

Ruben van Boxtel

1

0 references

author name string

Pim W Toonen

3

1 reference

7 August 2017

Roel Hermsen

5

1 reference

7 August 2017

Alain de Bruin

6

1 reference

7 August 2017

Edwin Cuppen

7

1 reference

7 August 2017

language of work or name

English

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publication date

18 August 2011

1 reference

The American Journal of Pathology

7 August 2017

published in

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7 August 2017

volume

179

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7 August 2017

issue

4

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7 August 2017

page(s)

1616-1622

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Beyond knockout rats: new insights into finer genome manipulation in rats

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Rat traps: filling the toolbox for manipulating the rat genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Production of p53 gene knockout rats by homologous recombination in embryonic stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

ENU mutagenesis to generate genetically modified rat models

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Knockout rats via embryo microinjection of zinc-finger nucleases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Transcriptional control of human p53-regulated genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Characterizing a rat Brca2 knockout model

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Production of knockout rats using ENU mutagenesis and a yeast-based screening assay

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Tumor suppressor genes in normal and malignant hematopoiesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Tumourigenesis associated with the p53 tumour suppressor gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Tumor spectrum analysis in p53-mutant mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Murine models of neoplasia: functional analysis of the tumour suppressor genes Rb-1 and p53.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

p53 mutations in human cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Profile of early occurring spontaneous tumors in Han Wistar rats

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181367

Functional genomics and rat models

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21854749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Very low incidence of p53 antibodies in adult non-Hodgkin's lymphoma and multiple myeloma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21854749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.AJPATH.2011.06.036

1 reference

7 August 2017

1 reference

7 August 2017

1 reference