(Q46640847)

23 December 2017

title

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis (English)

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23 December 2017

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Ruben van Boxtel

1

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author name string

Pim W Toonen

2

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23 December 2017

Henk S van Roekel

3

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23 December 2017

Mark Verheul

4

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23 December 2017

Bart M G Smits

5

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23 December 2017

Jeroen Korving

6

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23 December 2017

Alain de Bruin

7

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23 December 2017

Edwin Cuppen

8

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23 December 2017

language of work or name

English

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publication date

15 April 2008

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23 December 2017

published in

Carcinogenesis

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23 December 2017

volume

29

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23 December 2017

issue

6

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23 December 2017

page(s)

1290-1297

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23 December 2017

DNA mismatch correction in a defined system

cites work

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Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level

21 January 2018

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Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility

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Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

21 January 2018

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Familial endometrial cancer in female carriers of MSH6 germline mutations

21 January 2018

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

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Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

21 January 2018

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HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

21 January 2018

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Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

21 January 2018

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Impact of genomics on research in the rat.

21 January 2018

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Rat genetics: the next episode

21 January 2018

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Genome sequence of the Brown Norway rat yields insights into mammalian evolution

21 January 2018

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Production of knockout rats using ENU mutagenesis and a yeast-based screening assay

21 January 2018

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

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A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

21 January 2018

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Inherited susceptibility to colorectal cancer

21 January 2018

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Transgenic mouse models of human breast cancer

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Characterizing a rat Brca2 knockout model

21 January 2018

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PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing

21 January 2018

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The structural basis for the mutagenicity of O6-methyl-guanine lesions

21 January 2018

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21 January 2018

DNA replication fidelity

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Multiple mutations and cancer

21 January 2018

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Patterns of somatic mutation in human cancer genomes

21 January 2018

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Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium

21 January 2018

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Mouse models for human DNA mismatch-repair gene defects

21 January 2018

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MSH2 deficient mice are viable and susceptible to lymphoid tumours

21 January 2018

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Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations

21 January 2018

1 reference

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Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Loss of DNA mismatch repair function and cancer predisposition in the mouse: animal models for human hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN094

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGN094

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23 December 2017

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23 December 2017