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The role for autophagy in cancer
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The role for autophagy in cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
main subject
autophagy
0 references
author
Eileen White
object named as
Eileen White
series ordinal
1
0 references
language of work or name
English
0 references
publication date
2 January 2015
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
volume
125
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
page(s)
42-46
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stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
cites work
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations
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Autophagy is required for glucose homeostasis and lung tumor maintenance
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12 July 2018
Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers
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12 July 2018
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
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PubMed Central
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12 July 2018
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.
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PubMed Central
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12 July 2018
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion
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PubMed Central
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12 July 2018
ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss
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12 July 2018
Mutational landscape of the essential autophagy gene BECN1 in human cancers
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PubMed Central
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12 July 2018
Discovery and saturation analysis of cancer genes across 21 tumour types
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PubMed Central
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12 July 2018
SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer
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PubMed Central
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12 July 2018
Autophagy-mediated tumor promotion
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PubMed Central
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12 July 2018
p53 status determines the role of autophagy in pancreatic tumour development
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PubMed Central
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12 July 2018
Exploiting the bad eating habits of Ras-driven cancers
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12 July 2018
Autophagy in infection, inflammation, and immunity
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12 July 2018
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors
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12 July 2018
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Inflammation and liver tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer.
1 reference
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PubMed Central
reference URL
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12 July 2018
Regulation of mTORC1 and its impact on gene expression at a glance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Cancer genome landscapes
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PubMed Central
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12 July 2018
Autophagy in human health and disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Deconvoluting the context-dependent role for autophagy in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
p62: a versatile multitasker takes on cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Autophagy: renovation of cells and tissues
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Autophagy-deficient mice develop multiple liver tumors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Pancreatic cancers require autophagy for tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
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12 July 2018
Principles and current strategies for targeting autophagy for cancer treatment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Learning from oncocytic tumors: Why choose inefficient mitochondria?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy suppresses tumorigenesis through elimination of p62
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy regulates lipid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy in the Pathogenesis of Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy suppresses tumor progression by limiting chromosomal instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
12 July 2018
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
26 September 2018
Autophagy can contribute to cell death when combining targeted therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
26 September 2018
A dual role for autophagy in a murine model of lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4382247
retrieved
15 November 2018
Identifiers
DOI
10.1172/JCI73941
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
PMCID
4382247
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
PubMed ID
25654549
1 reference
stated in
Europe PubMed Central
PubMed ID
25654549
retrieved
7 August 2017
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