Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35265605)
Watch
English
Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
title
Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
main subject
varenicline
1 reference
based on heuristic
inferred from title
author
Henry Lester
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author name string
S C R Lummis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
A J Thompson
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
M Bencherif
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
language of work or name
English
0 references
publication date
20 July 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
published in
Journal of Pharmacology and Experimental Therapeutics
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
volume
339
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
page(s)
125-131
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
cites work
Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
An efficient and information-rich biochemical method design for fragment library screening on ion channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
The structural basis of function in Cys-loop receptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
The 5-HT3B subunit is a major determinant of serotonin-receptor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Mechanisms of vomiting induced by serotonin-3 receptor agonists in the cat: effect of vagotomy, splanchnicectomy or area postrema lesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
27 July 2018
Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers: a multicenter, randomized, double-blind, placebo-controlled, parallel-group study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
The 5-HT3 receptor as a therapeutic target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
FlexStation examination of 5-HT3 receptor function using Ca2+ - and membrane potential-sensitive dyes: advantages and potential problems.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
Expression of 5-HT3A receptors in cells of the immune system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186289
retrieved
26 September 2018
Multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy smokers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21775477
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A novel series of [3.2.1] azabicyclic biaryl ethers as α3β4 and α6/4β4 nicotinic receptor agonists
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21775477
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21775477
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1124/JPET.111.185306
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMC publication ID
3186289
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed publication ID
21775477
1 reference
stated in
Europe PubMed Central
PMC publication ID
3186289
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775477%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
ResearchGate publication ID
51508038
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit