(Q35266412)

English

Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels (English)

1 reference

Europe PubMed Central

7 August 2017

author name string

Maya Gur

1

1 reference

Europe PubMed Central

7 August 2017

Roy Kahn

2

1 reference

Europe PubMed Central

7 August 2017

Izhar Karbat

3

1 reference

Europe PubMed Central

7 August 2017

Noa Regev

4

1 reference

Europe PubMed Central

7 August 2017

Jinti Wang

5

1 reference

Europe PubMed Central

7 August 2017

William A Catterall

6

1 reference

Europe PubMed Central

7 August 2017

Dalia Gordon

7

1 reference

Europe PubMed Central

7 August 2017

Michael Gurevitz

8

1 reference

Europe PubMed Central

7 August 2017

language of work or name

0 references

publication date

8 August 2011

1 reference

Europe PubMed Central

7 August 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

7 August 2017

286

1 reference

Europe PubMed Central

7 August 2017

40

1 reference

Europe PubMed Central

7 August 2017

35209-35217

1 reference

Europe PubMed Central

7 August 2017

Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Deconstructing voltage sensor function and pharmacology in sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

NMR analysis of interaction of LqhalphaIT scorpion toxin with a peptide corresponding to the D4/S3-S4 loop of insect para voltage-gated sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Closing in on the resting state of the Shaker K(+) channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

How does voltage open an ion channel?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Sodium channel inactivation: molecular determinants and modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Molecular interaction of delta-conotoxins with voltage-gated sodium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Molecular basis of the high insecticidal potency of scorpion alpha-toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Mechanisms of sodium channel inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Domain 2 of Drosophila para voltage-gated sodium channel confers insect properties to a rat brain channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Interaction of scorpion alpha-toxins with cardiac sodium channels: binding properties and enhancement of slow inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Functional expression of Drosophila para sodium channels. Modulation by the membrane protein TipE and toxin pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Interaction between fast and slow inactivation in Skm1 sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Rapid voltage-dependent dissociation of scorpion alpha-toxins coupled to Na channel inactivation in amphibian myelinated nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Photoaffinity labeling of the receptor site for alpha-scorpion toxins on purified and reconstituted sodium channels by a new toxin derivative.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

Binding of scorpion toxin to receptor sites associated with sodium channels in frog muscle. Correlation of voltage-dependent binding with activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

27 July 2018

The insect voltage-gated sodium channel as target of insecticides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider delta-atracotoxin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Positions under positive selection--key for selectivity and potency of scorpion alpha-toxins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Modulation of the skeletal muscle sodium channel alpha-subunit by the beta 1-subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Effect of depolarization on binding kinetics of scorpion alpha-toxin highlights conformational changes of rat brain sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259507

21 January 2018

Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

26 September 2018

The position of the fourth segment of domain 4 determines status of the inactivation gate in Na+ channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186375

26 September 2018

Modulation of cloned skeletal muscle sodium channels by the scorpion toxins Lqh II, Lqh III, and Lqh alphaIT

1 reference

https://pubmed.ncbi.nlm.nih.gov/21832067

12 December 2020

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Identifiers

10.1074/JBC.M111.259507

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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