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Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
title
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
main subject
autophagy
0 references
metformin
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author
Thomas Botton
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Michaël Cerezo
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Guillaume Robert
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Frédéric Luciano
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Alexandre Puissant
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Corine Bertolotto
series ordinal
9
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Sophie Tartare-Deckert
series ordinal
11
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Philippe Bahadoran
series ordinal
12
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Patrick Auberger
series ordinal
13
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Robert Ballotti
series ordinal
14
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
author name string
T Tomic
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
P Gounon
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
M Allegra
series ordinal
8
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
J-M Bereder
series ordinal
10
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
S Rocchi
series ordinal
15
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
publication date
1 September 2011
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
published in
Cell Death and Disease
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
page(s)
e199
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
cites work
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PubMed Central
reference URL
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Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of Akt.
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PubMed Central
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12 July 2018
Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Tumor-reactive CD4+ CD8αβ+ CD103+ αβT cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers.
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12 July 2018
Metformin and other biguanides in oncology: advancing the research agenda
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PubMed Central
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12 July 2018
AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Tumor suppressive functions of p53
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Self-killing of melanoma cells by cytosolic delivery of dsRNA: wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in tumor cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Metformin induces unique biological and molecular responses in triple negative breast cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Anti- and pro-tumor functions of autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
In vitro and in vivo anti-melanoma effects of ciglitazone.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Metformin induces apoptosis of pancreatic cancer cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Control of autophagy by oncogenes and tumor suppressor genes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Cathepsins: key modulators of cell death and inflammatory responses
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PubMed Central
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12 July 2018
Does autophagy have a license to kill mammalian cells?
1 reference
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PubMed Central
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12 July 2018
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
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PubMed Central
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12 July 2018
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Self-eating and self-killing: crosstalk between autophagy and apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
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12 July 2018
Epidemiology and prevention of cutaneous melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Regulation and role of autophagy in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Role of AMP-activated protein kinase in mechanism of metformin action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Metformin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
12 July 2018
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
26 September 2018
PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186904
retrieved
26 September 2018
Lactic acidosis in metformin therapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21881601
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The blooming of the French lilac
1 reference
stated in
COCI
retrieved
12 April 2024
reference URL
https://opencitations.net/index/api/v1/citations/10.1172/JCI14178
Identifiers
DOI
10.1038/CDDIS.2011.86
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Fatcat ID
release_osvhv2vqxvdw5a7tg53qsxt57a
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/osvhv2vqxvdw5a7tg53qsxt57a
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3186904
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
PubMed ID
21881601
1 reference
stated in
Europe PubMed Central
PMCID
3186904
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21881601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
ResearchGate publication ID
51609275
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