(Q35276891)

7 August 2017

title

Transmembrane segments of nascent polytopic membrane proteins control cytosol/ER targeting during membrane integration (English)

1 reference

7 August 2017

main subject

transmembrane protein

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1 reference

Pen-Jen Lin

1

1 reference

7 August 2017

Candice G Jongsma

series ordinal

2

1 reference

7 August 2017

Shuren Liao

series ordinal

3

1 reference

7 August 2017

Arthur E Johnson

series ordinal

4

1 reference

7 August 2017

language of work or name

English

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publication date

26 September 2011

1 reference

7 August 2017

published in

Journal of Cell Biology

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7 August 2017

volume

195

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7 August 2017

issue

1

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7 August 2017

page(s)

41-54

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Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the translocon

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Crystal structure of the eukaryotic ribosome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Cellular mechanisms of membrane protein folding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

The structural and functional coupling of two molecular machines, the ribosome and the translocon

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Fluorescence approaches for determining protein conformations, interactions and mechanisms at membranes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Cotranslational membrane protein biogenesis at the endoplasmic reticulum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

X-ray structure of a protein-conducting channel

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Structural insight into the role of the ribosomal tunnel in cellular regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

A new role for BiP: closing the aqueous translocon pore during protein integration into the ER membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

The structural basis of ribosome activity in peptide bond synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

The translocon: a dynamic gateway at the ER membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Membrane protein folding and stability: physical principles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Effects of nucleotide- and aurodox-induced changes in elongation factor Tu conformation upon its interactions with aminoacyl transfer RNA. A fluorescence study.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Nepsilon-acetyllysine transfer ribonucleic acid: a biologically active analogue of aminoacyl transfer ribonucleic acids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

Cell-free translation of messenger RNA in a wheat germ system.

12 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

A trans-membrane segment inside the ribosome exit tunnel triggers RAMP4 recruitment to the Sec61p translocase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Importin-alpha-16 is a translocon-associated protein involved in sorting membrane proteins to the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Mapping the electrostatic potential within the ribosomal exit tunnel

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187712

The Structure of Ribosome-Channel Complexes Engaged in Protein Translocation

26 September 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201103117

The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process

21 January 2018

1 reference

12 December 2020

The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation

1 reference

12 December 2020

A method for on-line background subtraction in frequency domain fluorometry

1 reference

12 December 2020

Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration

1 reference

12 December 2020

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

1 reference

12 December 2020

Slow translocon gating causes cytosolic exposure of transmembrane and lumenal domains during membrane protein integration

1 reference

12 December 2020

BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation

1 reference

12 December 2020

The environment of nascent secretory and membrane proteins at the endoplasmic reticulum membrane during translocation and integration

1 reference

12 December 2020

The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.201103117

1 reference

7 August 2017

1 reference

7 August 2017

1 reference