(Q35277863)

English

Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine

scientific article published on December 31, 1992

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scholarly article

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Europe PubMed Central

7 August 2017

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Europe PubMed Central

Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine (English)

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Europe PubMed Central

7 August 2017

Alzheimer's disease

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post-translational protein modification

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18 September 2022

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Greengard P

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J. D. Buxbaum

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18 September 2022

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A. C. Nairn

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18 September 2022

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S. E. Gandy

1

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18 September 2022

G. L. Caporaso

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18 September 2022

T. V. Ramabhadran

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18 September 2022

T. Suzuki

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18 September 2022

C. Nordstedt

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18 September 2022

K. Iverfeldt

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18 September 2022

A. J. Czernik

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18 September 2022

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publication date

1 December 1992

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31 December 1992

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18 September 2022

Annals of the New York Academy of Sciences

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Europe PubMed Central

7 August 2017

674

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7 August 2017

203-217

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Europe PubMed Central

7 August 2017

New perspectives on Alzheimer's disease

1 reference

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21 January 2018

Aberrant neurofilament phosphorylation in Alzheimer disease

1 reference

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21 January 2018

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

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21 January 2018

Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation

1 reference

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

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Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

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21 January 2018

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

1 reference

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A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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21 January 2018

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

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21 January 2018

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

1 reference

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21 January 2018

Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors

1 reference

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21 January 2018

Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process

1 reference

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Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms

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21 January 2018

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

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21 January 2018

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

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21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

The molecular pathology of Alzheimer's disease

1 reference

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Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

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21 January 2018

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities

1 reference

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21 January 2018

Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27489.X

21 January 2018

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

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21 January 2018

Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment

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Formation of beta-amyloid protein deposits in brains of transgenic mice

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Deciphering Alzheimer's disease: the amyloid precursor protein yields new clues

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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Amyloid beta protein enhances the survival of hippocampal neurons in vitro

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Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease

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Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

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An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

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Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms

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Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

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12 October 2022

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Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles.

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Familial Alzheimer's disease

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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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Identifiers

10.1111/J.1749-6632.1992.TB27489.X

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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