(Q35288875)

7 August 2017

title

PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway (English)

1 reference

7 August 2017

1 reference

Nerium oleander

1 reference

Yong Pan

1

1 reference

7 August 2017

Patrea Rhea

2

1 reference

7 August 2017

Lin Tan

3

1 reference

7 August 2017

Carrie Cartwright

4

1 reference

7 August 2017

Ho-Jeong Lee

5

1 reference

7 August 2017

Murali K Ravoori

6

1 reference

7 August 2017

Crandell Addington

7

1 reference

7 August 2017

Mihai Gagea

8

1 reference

7 August 2017

Vikas Kundra

9

1 reference

7 August 2017

Sun-Jin Kim

10

1 reference

7 August 2017

Robert A Newman

11

1 reference

7 August 2017

Peiying Yang

12

1 reference

7 August 2017

language of work or name

1 reference

6 December 2014

1 reference

Investigational New Drugs

7 August 2017

published in

1 reference

7 August 2017

volume

33

1 reference

7 August 2017

issue

2

1 reference

7 August 2017

page(s)

271-279

1 reference

Creative Commons Attribution 4.0 International

7 August 2017

copyright license

start time

6 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Beyond first-line chemotherapy for advanced pancreatic cancer: an expanding array of therapeutic options?

12 July 2018

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12 July 2018

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Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

12 July 2018

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Current understanding of the molecular biology of pancreatic neuroendocrine tumors

12 July 2018

1 reference

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A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells.

12 July 2018

1 reference

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12 July 2018

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12 July 2018

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Personalized chemotherapy profiling using cancer cell lines from selectable mice

12 July 2018

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Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.

12 July 2018

1 reference

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Cellular location and expression of Na+, K+ -ATPase α subunits affect the anti-proliferative activity of oleandrin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis

12 July 2018

1 reference

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Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides

12 July 2018

1 reference

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nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer

12 July 2018

1 reference

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Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum.

12 July 2018

1 reference

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Pleiotropic effects of cardioactive glycosides.

12 July 2018

1 reference

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12 July 2018

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Oleandrin-mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug targets

12 July 2018

1 reference

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Novel therapeutic applications of cardiac glycosides

12 July 2018

1 reference

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Cardiac glycosides as novel cancer therapeutic agents

12 July 2018

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The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas

12 July 2018

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Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside.

12 July 2018

1 reference

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Cardiac glycosides in cancer research and cancer therapy.

12 July 2018

1 reference

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Cytotoxic effects of leaf, stem and root extracts of Nerium oleander on leukemia cell lines and role of the p-glycoprotein in this effect.

12 July 2018

1 reference

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Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Oleandrin induces apoptosis in human, but not in murine cells: dephosphorylation of Akt, expression of FasL, and alteration of membrane fluidity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Oleandrin suppresses activation of nuclear transcription factor-κB and activator protein-1 and potentiates apoptosis induced by ceramide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

The effect of chronic digitoxin administration on the contractile state of normal and nonfailing hypertrophied myocardium

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models

12 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0190-6

Anvirzel, an extract of Nerium oleander, induces cell death in human but not murine cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0190-6

Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0190-6

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion markers in CD-1 mouse skin by oleandrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-014-0190-6

First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-κΒ and p70s6k, in patients with advanced solid tumors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387257

Confirmation of improved local-regional control with altered fractionation in head and neck cancer

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25476893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cardiac glycosides and breast cancer, revisited

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25476893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cardiac glycosides and breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25476893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10637-014-0190-6

1 reference

7 August 2017

1 reference

7 August 2017

1 reference