(Q35289128)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Direct measurement of the protein response to an electrostatic perturbation that mimics the catalytic cycle in ketosteroid isomerase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

4

Steven G Boxer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Santosh Kumar Jha

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Kelly J Gaffney

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

26 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

16612-16617

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

Concerted electron-proton transfer in the optical excitation of hydrogen-bonded dyes

13 February 2020

cites work

1 reference

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Characterizing the dynamics of functionally relevant complexes of formate dehydrogenase

27 July 2018

1 reference

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Decomposition of vibrational shifts of nitriles into electrostatic and hydrogen-bonding effects

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Impact of mutation on proton transfer reactions in ketosteroid isomerase: insights from molecular dynamics simulations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Solvation response along the reaction coordinate in the active site of ketosteroid isomerase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Proton affinity of the oxyanion hole in the active site of ketosteroid isomerase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Ultrafast solvation dynamics at binding and active sites of photolyases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Enzymatic transition states and dynamic motion in barrier crossing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Atomic detail of chemical transformation at the transition state of an enzymatic reaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

What determines the speed limit on enzyme catalysis?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Fast enzyme dynamics at the active site of formate dehydrogenase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Site-specific conversion of cysteine thiols into thiocyanate creates an IR probe for electric fields in proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Electrostatic basis for enzyme catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Electric fields at the active site of an enzyme: direct comparison of experiment with theory.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Dynamical contributions to enzyme catalysis: critical tests of a popular hypothesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Enzymatic mechanisms for catalysis of enolization: ketosteroid isomerase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Challenges in enzyme mechanism and energetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Impact of enzyme motion on activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Probing protein electrostatics with a synthetic fluorescent amino acid.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Transition path sampling: throwing ropes over rough mountain passes, in the dark.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

A view at the millennium: the efficiency of enzymatic catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Network of coupled promoting motions in enzyme catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Dynamics of enzymatic reactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Iron-carbonyl bond geometries of carboxymyoglobin and carboxyhemoglobin in solution determined by picosecond time-resolved infrared spectroscopy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

27 July 2018

1 reference

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Enzymes work by solvation substitution rather than by desolvation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Energetics of 3-oxo-delta 5-steroid isomerase: source of the catalytic power of the enzyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Electrostatic effects in proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Energetics of enzyme catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189056

Why enzymes are proficient catalysts: beyond the Pauling paradigm

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

How enzyme dynamics helps catalyze a reaction in atomic detail: a transition path sampling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Dynamic effects on reaction rates in a Michael addition catalyzed by chalcone isomerase. Beyond the frozen environment approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

21 January 2018

Waterlogged Molecules

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

The catalytic power of ketosteroid isomerase investigated by computer simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Solute solvent dynamics and energetics in enzyme catalysis: the S(N)2 reaction of dehalogenase as a general benchmark.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Structure and enzymology of Delta5-3-ketosteroid isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Interrogating conformationally dependent electron-transfer dynamics via ultrafast visible pump/IR probe spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Ultrafast vibrational Stark-effect spectroscopy: exploring charge-transfer reactions by directly monitoring the solvation shell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Charge transfer in photoacids observed by stark spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Nitrile Bonds as Infrared Probes of Electrostatics in Ribonuclease S

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Investigation of the excited state structure of DCM via ultrafast electronic pump/vibrational probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Role of Catalytic Residues in Enzymatic Mechanisms of Homologous Ketosteroid Isomerases†,‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1113874108

Solvation, reorganization energy, and biological catalysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21949360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A transition path sampling study of the reaction catalyzed by the enzyme chorismate mutase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21949360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding of CO to myoglobin from a heme pocket docking site to form nearly linear Fe-C-O

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21949360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1113874108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21949360%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21949360

1 reference