(Q35335855)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

review article

1 reference

title

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Martin K Lotz

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

2 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Rheumatology

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

579-587

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrrheum.2011.109

9 February 2020

exact match

0 references

cites work

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Mammalian target of rapamycin (mTOR) inhibitors: potential uses and a review of haematological adverse effects

27 July 2018

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The role of mitochondria in osteoarthritis

27 July 2018

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Selective autophagy mediated by autophagic adapter proteins

27 July 2018

1 reference

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Chemical and/or biological therapeutic strategies to ameliorate protein misfolding diseases

27 July 2018

1 reference

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Bone and cartilage in osteoarthritis: is what's best for one good or bad for the other?

27 July 2018

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Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

27 July 2018

1 reference

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Recommendations for the use of preclinical models in the study and treatment of osteoarthritis.

27 July 2018

1 reference

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Can autophagy promote longevity?

27 July 2018

1 reference

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Disease modifying osteoarthritis drugs: facing development challenges and choosing molecular targets

27 July 2018

1 reference

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Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

27 July 2018

1 reference

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OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.

27 July 2018

1 reference

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Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.

27 July 2018

1 reference

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The genetic epidemiology of osteoarthritis

27 July 2018

1 reference

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Glucosamine induces autophagy via an mTOR-independent pathway

27 July 2018

1 reference

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ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

27 July 2018

1 reference

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Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The regulation of aging: does autophagy underlie longevity?

27 July 2018

1 reference

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Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates

27 July 2018

1 reference

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Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging

27 July 2018

1 reference

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Regulation of apoptosis by the unfolded protein response.

27 July 2018

1 reference

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

27 July 2018

1 reference

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The TOR pathway comes of age

27 July 2018

1 reference

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Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis

27 July 2018

1 reference

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Biomechanical, structural, and biochemical indices of degenerative and osteoarthritic deterioration of adult human articular cartilage of the femoral condyle

27 July 2018

1 reference

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OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

27 July 2018

1 reference

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Design of aging intervention studies: the NIA interventions testing program

27 July 2018

1 reference

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Evolution of Atg1 function and regulation

27 July 2018

1 reference

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Regulation of the aging process by autophagy

27 July 2018

1 reference

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Biological and chemical approaches to diseases of proteostasis deficiency

27 July 2018

1 reference

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Developments in the clinical understanding of osteoarthritis

27 July 2018

1 reference

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Protein homeostasis and aging: taking care of proteins from the cradle to the grave

27 July 2018

1 reference

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Molecular mechanisms of cartilage destruction in osteoarthritis.

27 July 2018

1 reference

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27 July 2018

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Autophagy and aging: keeping that old broom working

27 July 2018

1 reference

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Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

27 July 2018

1 reference

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Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

27 July 2018

1 reference

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Autophagy-physiology and pathophysiology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy fights disease through cellular self-digestion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Potential therapeutic applications of autophagy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Protein turnover via autophagy: implications for metabolism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Glucosamine-induced increase in Akt phosphorylation corresponds to increased endoplasmic reticulum stress in astroglial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy is activated for cell survival after endoplasmic reticulum stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy and aging: the importance of maintaining "clean" cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy and signaling: their role in cell survival and cell death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy: dual roles in life and death?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Overview of caloric restriction and ageing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The future of aging therapies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Use of complementary therapies among primary care clinic patients with arthritis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The mechanobiology of articular cartilage development and degeneration.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Zonal and topographical differences in articular cartilage gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Aging theories of primary osteoarthritis: from epidemiology to molecular biology.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Two ubiquitin-like conjugation systems essential for autophagy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The surface of articular cartilage contains a progenitor cell population

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Lipofuscin: mechanisms of age-related accumulation and influence on cell function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Oxidants, oxidative stress and the biology of ageing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Physiological functions of autophagy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The unfolded protein response in health and disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy contributes to degradation of Hirano bodies

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Changes in surgical loads and economic burden of hip and knee replacements in the US: 1997-2004.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The effect of glycosaminoglycan loss on chondrocyte viability: a study on porcine cartilage explants

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Osteoarthritis in the context of ageing and evolution. Loss of chondrocyte differentiation block during ageing

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Update on the biology of the chondrocyte and new approaches to treating cartilage diseases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Autophagic programmed cell death by selective catalase degradation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Indentation testing of human cartilage: sensitivity to articular surface degeneration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Rates and outcomes of primary and revision total hip replacement in the United States medicare population

26 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

26 September 2018

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192496

The effects of specific medical conditions on the functional limitations of elders in the Framingham Study

26 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Glucosamine and chondroitin sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

The utility of nutraceuticals in the treatment of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Recent progress toward biomarker identification in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Risk factors for falls in a community-based prospective study of people 70 years and older

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Use of alternative therapies by older adults with osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Emerging drugs for osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Zonal variations in the three-dimensional morphology of the chondron measured in situ using confocal microscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

Lifelong diet restriction and radiographic evidence of osteoarthritis of the hip joint in dogs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.109

31 March 2020

Identifiers

DOI

10.1038/NRRHEUM.2011.109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808292%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21808292

1 reference