(Q35363763)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

In vitro and in vivo activities of novel, semisynthetic thiopeptide inhibitors of bacterial elongation factor Tu (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

24

1 reference

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9 February 2020

author name string

J A Leeds

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

M J LaMarche

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

J T Brewer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

S M Bushell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

G Deng

5

1 reference

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9 February 2020

J M Dewhurst

6

1 reference

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9 February 2020

J Dzink-Fox

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

E Gangl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

A Jain

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

L Lee

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

M Lilly

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

K Manni

12

1 reference

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9 February 2020

S Mullin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

G Neckermann

14

1 reference

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9 February 2020

C Osborne

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

D Palestrant

16

1 reference

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9 February 2020

M A Patane

17

1 reference

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9 February 2020

A Raimondi

18

1 reference

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9 February 2020

S Ranjitkar

19

1 reference

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9 February 2020

E M Rann

20

1 reference

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9 February 2020

M Sachdeva

21

1 reference

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9 February 2020

J Shao

22

1 reference

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9 February 2020

S Tiamfook

23

1 reference

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9 February 2020

D Yu

25

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

8 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

Antimicrobial Agents and Chemotherapy

9 February 2020

published in

1 reference

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9 February 2020

volume

55

1 reference

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9 February 2020

issue

11

1 reference

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9 February 2020

page(s)

5277-5283

1 reference

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Confronting the challenges of natural product-based antifungal discovery

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Future treatment options for Gram-positive infections--looking ahead

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Drug discovery and natural products: end of an era or an endless frontier?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Elongation factor Tu-targeted antibiotics: four different structures, two mechanisms of action

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Recent developments in antibacterial drug discovery: microbe-derived natural products--from collection to the clinic

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Natural products to drugs: natural product derived compounds in clinical trials

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Antimicrobial activities of chemically modified thiazolyl peptide antibiotic MDL 62,879 (GE2270A).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

In vitro activity of MDL 62,879 (GE2270 A) against aerobic gram-positive and anaerobic bacteria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

In vitro antimicrobial activity of a new antibiotic, MDL 62,879 (GE2270 A)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Kirromycin-induced modifications facilitate the separation of EF-Tu species and reveal intermolecular interactions.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

4-Aminothiazolyl analogues of GE2270 A: antibacterial lead finding.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Hypothesis-driven screening.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

Combinatorial modification of natural products: synthesis and in vitro analysis of derivatives of thiazole peptide antibiotic GE2270 A: A-ring modifications

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195004

26 September 2018

Identifiers

DOI

10.1128/AAC.00582-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21825297%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21825297

1 reference