(Q33234858)

24 July 2017

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title

Recent developments in antibacterial drug discovery: microbe-derived natural products--from collection to the clinic (English)

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24 July 2017

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Jennifer A Leeds

1

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24 July 2017

Esther K Schmitt

series ordinal

2

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24 July 2017

Philipp Krastel

series ordinal

3

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24 July 2017

language of work or name

English

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publication date

1 March 2006

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Expert Opinion on Investigational Drugs

24 July 2017

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24 July 2017

15

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24 July 2017

3

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24 July 2017

211-226

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Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors

24 July 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Natural products to drugs: natural product derived compounds in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Lessons from natural molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Target-oriented and diversity-oriented organic synthesis in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Recently approved and investigational antibiotics for treatment of severe infections caused by Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Mutations in the interdomain loop region of the tetA(A) tetracycline resistance gene increase efflux of minocycline and glycylcyclines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Tigecycline: what is it, and where should it be used?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Tigecycline is modified by the flavin-dependent monooxygenase TetX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Initiation of transcription in vitro is inhibited by lipiarmycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Antibiotic substances from Basidiomycetes+. VII. Clitocybe illudens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. Part 3: Chemical derivatization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. I. Taxonomy, isolation and characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Tripropeptin E, a new tripropeptin group antibiotic produced by Lysobacter sp. BMK333-48F3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

The manumycin-group metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Laboratory cultivation of widespread and previously uncultured soil bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Biotechnological prospects from metagenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Metagenomics for studying unculturable microorganisms: cutting the Gordian knot

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

New natural product families from an environmental DNA (eDNA) gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

bryA: an unusual modular polyketide synthase gene from the uncultivated bacterial symbiont of the marine bryozoan Bugula neritina

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Natural products in the process of finding new drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Fungal metabolite screening: database of 474 mycotoxins and fungal metabolites for dereplication by standardised liquid chromatography-UV-mass spectrometry methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

The evolving role of natural products in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

An MS/MS library on an ion-trap instrument for efficient dereplication of natural products. Different fragmentation patterns for [M + H]+ and [M + Na]+ ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

On-line coupling of high-performance liquid chromatography to a continuous-flow enzyme assay based on electrospray ionization mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Multitarget Affinity/Specificity Screening of Natural Products: Finding and Characterizing High-Affinity Ligands from Complex Mixtures by Using High-Performance Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Preparative LC-MS purification: improved compound-specific method optimization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

FT-ICR mass spectrometry in the drug discovery process

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Structure elucidation from 2D NMR spectra using the StrucEluc expert system: detection and removal of contradictions in the data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Recent developments in automated structure elucidation of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

LC-NMR coupling technology: recent advancements and applications in natural products analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Panel of Bacillus subtilis reporter strains indicative of various modes of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

A generally applicable, high-throughput screening-compatible assay to identify, evaluate, and optimize antimicrobial agents for drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

A genome-wide strategy for the identification of essential genes in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Mannopeptimycins, a novel class of glycopeptide antibiotics active against gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

The essence of total synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Chemical diversity through biotransformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Accessorizing natural products: adding to nature's toolbox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Natural products as a hunting ground for combinatorial chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Optimization of antibacterial cyclic decapeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Virtual Screening on Natural Products for Discovering Active Compounds and Target Information

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Molecular insights into aminoglycoside action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Improving on nature: antibiotics that target the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Mutational biosynthesis--a tool for the generation of structural diversity in the biosynthesis of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Manipulation and analysis of polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

New aminocoumarin antibiotics from genetically engineered Streptomyces strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Cometabolic reduction of bromate by a mixed culture of microorganisms using hydrogen gas in a gas-lift reactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

15-amido erythromycins: synthesis and in vitro activity of a new class of macrolide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Using genomics to deliver natural products from symbiotic bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Molecular characterization of the safracin biosynthetic pathway from Pseudomonas fluorescens A2-2: designing new cytotoxic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Metabolic engineering of aminocoumarins: inactivation of the methyltransferase gene cloP and generation of new clorobiocin derivatives in a heterologous host

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Production of the potent antibacterial polyketide erythromycin C in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Semi-synthetic DNA shuffling of aveC leads to improved industrial scale production of doramectin by Streptomyces avermitilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Streptomycin, a Substance Exhibiting Antibiotic Activity Against Gram-Positive and Gram-Negative Bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Ten thousand interactions for the molecular biologist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.3.211

Tripropeptins, novel antimicrobial agents produced by Lysobacter sp. I. Taxonomy, isolation and biological activities

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.1054

Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.567

Identifiers

DOI

10.1517/13543784.15.3.211

1 reference

24 July 2017

1 reference