(Q35370169)

8 August 2017

1 reference

title

Apoptosis in the development of the immune system: growth factors, clonal selection and bcl-2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1394795

22 September 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1394795

22 September 2022

3

G. T. Williams

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1394795

22 September 2022

author name string

McCarthy NJ

series ordinal

1

1 reference

8 August 2017

N. J. McCarthy

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1394795

22 September 2022

C. A. Smith

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1394795

22 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1394795

22 September 2022

publication date

1 September 1992

1 reference

Cancer and Metastasis Reviews

8 August 2017

published in

1 reference

8 August 2017

volume

11

1 reference

8 August 2017

issue

2

1 reference

8 August 2017

page(s)

157-178

1 reference

The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation

8 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00048062

Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00048062

Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I

21 January 2018

1 reference

12 December 2020

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes

1 reference

12 December 2020

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion

1 reference

12 December 2020

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1 reference

12 December 2020

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

1 reference

12 December 2020

Selective death of T cell receptor gamma/delta+ intraepithelial lymphocytes by apoptosis

1 reference

12 December 2020

The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.

1 reference

12 December 2020

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1 reference

12 December 2020

Rescue from programmed cell death in leukemic and normal myeloid cells

1 reference

12 December 2020

Antigen-driven selection of virgin and memory B cells

1 reference

12 December 2020

The differentiation of T lymphocytes. V. Evidence for intrathymic death of most thymocytes

1 reference

12 December 2020

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1 reference

12 December 2020

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

1 reference

12 December 2020

Phorbol esters activate protein kinase C and glucose transport and can replace the requirement for growth factor in interleukin-3-dependent multipotent stem cells

1 reference

12 December 2020

Oncogenic potential of bcl-2 demonstrated by gene transfer.

1 reference

12 December 2020

IL3-dependent cells die by apoptosis on removal of their growth factor

1 reference

12 December 2020

Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors

1 reference

12 December 2020

Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C

1 reference

12 December 2020

Growth of factor-dependent hemopoietic precursor cell lines

1 reference

12 December 2020

Specificity of gamma delta receptor bearing T cells.

1 reference

12 December 2020

The role of plasmacytoma growth factor in the in vitro responses of murine plasmacytoma cells

1 reference

12 December 2020

A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

1 reference

12 December 2020

Extrathymic selection of TCR gamma delta + T cells by class II major histocompatibility complex molecules

1 reference

12 December 2020

Molecular genetics of immunoglobulins.

1 reference

12 December 2020

Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome

1 reference

12 December 2020

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

12 December 2020

ELECTRON MICROSCOPE OBSERVATIONS ON TINGIBLE BODY MACROPHAGES IN MOUSE SPLEEN

1 reference

12 December 2020

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

1 reference

12 December 2020

Accessories or coreceptors?

1 reference

12 December 2020

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1 reference

12 December 2020

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

1 reference

12 December 2020

Self-tolerance to transgenic γδ T cells by intrathymic inactivation

1 reference

12 December 2020

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1 reference

12 December 2020

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

1 reference

12 December 2020

Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment

1 reference

12 December 2020

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

12 December 2020

The evolution of B-cell clones

1 reference

12 December 2020

Signalling in B cells

1 reference

12 December 2020

Failure of T cell receptor Vβ negative selection in murine intestinal intra-epithelial lymphocytes

1 reference

12 December 2020

Heat shock proteins as antigens for gamma delta T cells

1 reference

12 December 2020

Differential response of malignant human B-cells to anti-IgM immunoglobulin (anti-mu) and B-cell growth factor: unique direct cytotoxicity of anti-mu on prolymphocytic leukemia cells.

1 reference

12 December 2020

Expression of a fetal γδ T-cell receptor in adult mice triggers a non-MHC-linked form of selective depletion

1 reference

12 December 2020

Expression of the murine proto-oncogene bcl-2 is stage specific and cell-type specific.

1 reference

12 December 2020

Differential sensitivity of human B cell subsets to activation signals delivered by anti-mu antibody and proliferative signals delivered by a monoclonal B cell growth factor

1 reference

12 December 2020

Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance

1 reference

12 December 2020

Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration

1 reference

12 December 2020

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1 reference

12 December 2020

T-cell lineages, repertoire selection and tolerance induction

1 reference

12 December 2020

T-cell differentiation is influenced by thymic microenvironments

1 reference

12 December 2020

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

1 reference

12 December 2020

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

1 reference

12 December 2020

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1 reference

12 December 2020

The centre of hypermutation

1 reference

12 December 2020

T-cell antigen receptor genes and T-cell recognition

1 reference

12 December 2020

T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells

1 reference

12 December 2020

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores

1 reference

12 December 2020

Effects of GM-CSF deprivation on precursors of granulocytes and macrophages

1 reference

12 December 2020

Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice

1 reference

12 December 2020

Ultrastructure of the rat thymus

1 reference

12 December 2020

Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells

1 reference

12 December 2020

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1 reference

12 December 2020

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1 reference

12 December 2020

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1 reference

12 December 2020

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1 reference

12 December 2020

IL-2 protects against anti-CD3-induced cell death in human medullary thymocytes.

1 reference

12 December 2020

Calcium-activated DNA fragmentation kills immature thymocytes

1 reference

12 December 2020

A new cytokine receptor superfamily

1 reference

12 December 2020

Thy-1+ epidermal cells in nude mice are distinct from their counterparts in thymus-bearing mice. A study of morphology, function, and T cell receptor expression

1 reference

12 December 2020

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

12 December 2020

Phorbol esters inhibit apoptosis in IL-2-dependent T lymphocytes

1 reference

12 December 2020

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

1 reference

12 December 2020

Somatic generation of antibody diversity

1 reference

12 December 2020

Effects of the steel gene product on mouse primordial germ cells in culture

1 reference

12 December 2020

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1 reference

12 December 2020

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

12 December 2020

Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters

1 reference

12 December 2020

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1 reference

12 December 2020

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 December 2020

Suppression of programmed death and G1 arrest in B-cell hybridomas by interleukin-6 is not accompanied by altered expression of immediate early response genes

1 reference

12 December 2020

Germinal centers develop oligoclonally

1 reference

12 December 2020

T lymphocytes in infectious mononucleosis. II. Response in vitro to interleukin-2 and establishment of T cell lines

1 reference

12 December 2020

Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations.

1 reference

12 December 2020

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

1 reference

12 December 2020

Immunological tolerance: new approaches using transgenic mice

1 reference

12 December 2020

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.

1 reference

12 December 2020

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

1 reference

12 December 2020

Bcl-2: B cell life, death and neoplasia

1 reference

12 December 2020

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation

1 reference

12 December 2020

Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis

1 reference

12 December 2020

BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense

1 reference

12 December 2020

Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis

1 reference

12 December 2020

Towards an integrated view of thymopoiesis

1 reference

12 December 2020

Functional anatomy of germinal centers

1 reference

12 December 2020

Programmed cell death: apoptosis and oncogenesis.

1 reference

12 December 2020

Epstein-Barr virus BHRF1 gene but not the cellular protooncogenebcl-2 is expressed in ataxia-telangiectasia lymphoblastoid lines

1 reference

12 December 2020

Requirement for mast cell growth factor for primordial germ cell survival in culture

1 reference

12 December 2020

The B-cell antigen receptor complex

1 reference

12 December 2020

Death of serum-free mouse embryo cells caused by epidermal growth factor deprivation is prevented by cycloheximide, 12-O-tetradecanoylphorbol-13-acetate, or vanadate

1 reference

12 December 2020

Direct sequence analysis of the 14q+ and 18q- chromosome junctions in follicular lymphoma

1 reference

12 December 2020

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

12 December 2020

Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms

1 reference

12 December 2020

Control of red cell production: the roles of programmed cell death (apoptosis) and erythropoietin

1 reference

12 December 2020

Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex

1 reference

12 December 2020

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

1 reference

12 December 2020

Programmed death of autoreactive thymocytes.

1 reference

12 December 2020

Antigen-induced apoptosis in developing T cells: a mechanism for negative selection of the T cell receptor repertoire

1 reference

12 December 2020

Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.

1 reference

12 December 2020

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1 reference

12 December 2020

Recombinant 25-kDa CD23 and interleukin 1α promote the survival of germinal center B cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis

1 reference

12 December 2020

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

1 reference

12 December 2020

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1 reference

12 December 2020

Separate lineages of T cells expressing the alpha beta and gamma delta receptors

1 reference

12 December 2020

Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb).

1 reference

12 December 2020

Rat "first-wave" mature thymocytes: cycling lymphoblasts that are sensitive to activation-induced cell death but rescued by interleukin 2

1 reference

12 December 2020

Regulation of immunoglobulin gene rearrangement and expression

1 reference

12 December 2020

CD77: an antigen of germinal center B cells entering apoptosis

1 reference

12 December 2020

Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes

1 reference

12 December 2020

Binding site for IgE of the human lymphocyte low-affinity Fc epsilon receptor (Fc epsilon RII/CD23) is confined to the domain homologous with animal lectins

1 reference

12 December 2020

Anti-immunoglobulin antibodies induce apoptosis in immature B cell lymphomas

1 reference

12 December 2020

Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene

1 reference

12 December 2020

Positive selection of the T cell repertoire: where and when does it occur?

1 reference

12 December 2020

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

12 December 2020

Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras

1 reference

12 December 2020

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1 reference

12 December 2020

Normal and neoplastic human plasma cells express bcl-2 antigen.

1 reference

12 December 2020

Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners

1 reference

12 December 2020

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

12 December 2020

Prevention of apoptosis by a baculovirus gene during infection of insect cells

1 reference

12 December 2020

Mechanism of antigen-driven selection in germinal centres

1 reference

12 December 2020

The neurotrophic theory and naturally occurring motoneuron death

1 reference

12 December 2020

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1 reference

12 December 2020

The molecular and cellular basis of affinity maturation in the antibody response

1 reference

12 December 2020

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

12 December 2020

Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells.

1 reference

12 December 2020

Cellular interactions between 3T3 cells and interleukin-3-dependent multipotent haemopoietic cells: a model system for stromal-cell-mediated haemopoiesis

1 reference

12 December 2020

IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells.

1 reference

12 December 2020

Bcl-2 maintains B cell memory

1 reference

12 December 2020

The reciprocal partners of both the t(14; 18) and the t(11; 14) translocations involved in B-cell neoplasms are rearranged by the same mechanism

1 reference

12 December 2020

Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.

1 reference

12 December 2020

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

12 December 2020

T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor

1 reference

12 December 2020

Recent progress on the human bcl-2 gene involved in follicular lymphoma: characterization of the protein products

1 reference

12 December 2020

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

1 reference

12 December 2020

Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

1 reference

12 December 2020

Intraclonal generation of antibody mutants in germinal centres

1 reference

12 December 2020

Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1 reference

12 December 2020

Self-reactive gamma delta T cells are eliminated in the thymus

1 reference

12 December 2020

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

12 December 2020

Kinetics of mature T-cell development in the thymus

1 reference

12 December 2020

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

12 December 2020

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

12 December 2020

Murine T cells with invariant gamma delta antigen receptors: origin, repertoire, and specificity

1 reference

12 December 2020

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

1 reference

12 December 2020

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation

1 reference

12 December 2020

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

1 reference

12 December 2020

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00048062

1 reference

8 August 2017

1 reference