(Q35371427)

8 August 2017

title

Akt fine-tunes NF-κB-dependent gene expression during T cell activation (English)

1 reference

8 August 2017

0 references

1 reference

Jing Cheng

1

1 reference

8 August 2017

Binh Phong

2

1 reference

8 August 2017

David C Wilson

3

1 reference

8 August 2017

Raphael Hirsch

4

1 reference

8 August 2017

Lawrence P Kane

5

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8 August 2017

language of work or name

English

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publication date

23 August 2011

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8 August 2017

number of pages

10

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Journal of Biological Chemistry

inferred from page(s)

published in

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8 August 2017

volume

286

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8 August 2017

issue

41

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8 August 2017

page(s)

36076-36085

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Akti-1/2, an allosteric inhibitor of Akt 1 and 2, efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway.

8 August 2017

cites work

1 reference

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Selective transcription in response to an inflammatory stimulus

27 July 2018

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Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

27 July 2018

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Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

27 July 2018

1 reference

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AKT/PKB signaling: navigating downstream

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

27 July 2018

1 reference

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Post-translational modifications regulate distinct functions of CARMA1 and BCL10.

27 July 2018

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Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways

27 July 2018

1 reference

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Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice

27 July 2018

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CARMA1 is required for Akt-mediated NF-kappaB activation in T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

The Akt/PKB pathway: molecular target for cancer drug discovery

27 July 2018

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A TNF-induced gene expression program under oscillatory NF-kappaB control

27 July 2018

1 reference

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Stimulus specificity of gene expression programs determined by temporal control of IKK activity

27 July 2018

1 reference

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Oscillations in NF-kappaB signaling control the dynamics of gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors

27 July 2018

1 reference

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Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

27 July 2018

1 reference

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Post-transcriptional regulation of proinflammatory proteins.

27 July 2018

1 reference

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Anti-TNF-alpha therapies: the next generation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

Akt is TCL-ish: implications for B-cell lymphoma.

27 July 2018

1 reference

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

27 July 2018

1 reference

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Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo

27 July 2018

1 reference

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Two waves of nuclear factor kappaB recruitment to target promoters

27 July 2018

1 reference

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Post-transcriptional regulation of pro-inflammatory gene expression

27 July 2018

1 reference

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Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha

27 July 2018

1 reference

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Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

27 July 2018

1 reference

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Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195567

Induction of NF-kappaB by the Akt/PKB kinase

27 July 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.259549

Follistatin-like protein-1 is a novel proinflammatory molecule.

21 January 2018

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TNF-mediated inflammatory disease.

21 January 2018

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The specificity of JAK3 kinase inhibitors

21 January 2018

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Follistatin-like protein 1 promotes arthritis by up-regulating IFN-gamma

21 January 2018

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Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.259549

Circuitry of nuclear factor kappaB signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.259549

A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide

21 January 2018

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TNFalpha production by CD4(+) T cells predicts long-term increase in lesion load on MRI in MS.

21 January 2018

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The IKK NF-kappa B system: a treasure trove for drug development

21 January 2018

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Targeting Akt in cancer therapy

21 January 2018

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Multiple transcription factor profiling by enzyme-linked immunoassay

26 September 2018

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12 December 2020

Ex vivo characterization of the autoimmune T cell response in the HLA-DR1 mouse model of collagen-induced arthritis reveals long-term activation of type II collagen-specific cells and their presence in arthritic joints

1 reference

12 December 2020

NF-kappaB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis in vivo

1 reference

12 December 2020

Increase of CD4+TNF{alpha}+IL-2-T cells in cerebrospinal fluid of multiple sclerosis patients

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.259549

1 reference

8 August 2017

1 reference

8 August 2017

1 reference