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Structural biology of innate immunity
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25622194
retrieved
8 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Structural biology of innate immunity
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25622194
retrieved
8 August 2017
main subject
structural biology
1 reference
based on heuristic
inferred from title
author
Qian Yin
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
author name string
Tian-Min Fu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
Jixi Li
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
Hao Wu
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
publication date
22 January 2015
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25622194
retrieved
8 August 2017
published in
Annual Review of Immunology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
volume
33
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
page(s)
393-416
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
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The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING
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12 July 2018
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
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Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
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12 July 2018
Species-specific detection of the antiviral small-molecule compound CMA by STING
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Higher-order assemblies in a new paradigm of signal transduction
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12 July 2018
Structural basis for termination of AIM2-mediated signaling by p202
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12 July 2018
Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly
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12 July 2018
Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
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12 July 2018
Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
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12 July 2018
Molecular basis of NF-κB signaling
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12 July 2018
Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling
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12 July 2018
Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1
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12 July 2018
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5
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12 July 2018
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
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12 July 2018
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
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12 July 2018
MDA5 assembles into a polar helical filament on dsRNA.
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12 July 2018
Sensing of microbial molecular patterns by Toll-like receptors
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12 July 2018
Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I
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12 July 2018
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
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12 July 2018
Crystallographic characterization of mouse AIM2 HIN-200 domain bound to a 15 bp and an 18 bp double-stranded DNA.
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12 July 2018
Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
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12 July 2018
The structural basis for the sensing and binding of cyclic di-GMP by STING
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12 July 2018
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
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12 July 2018
Cyclic di-GMP sensing via the innate immune signaling protein STING
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12 July 2018
Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.
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12 July 2018
Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily
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12 July 2018
Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
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12 July 2018
Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
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12 July 2018
Regulation of inflammasome signaling
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12 July 2018
Helical assembly in the death domain (DD) superfamily
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12 July 2018
Structure of the activating IL-1 receptor signaling complex
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12 July 2018
Structural basis of TLR5-flagellin recognition and signaling
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12 July 2018
MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320 row detector computed tomography: design and implementation of the CORE320 multicenter, multinational diagnostic study.
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12 July 2018
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structural Insights into RNA Recognition by RIG-I
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling
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PubMed Central
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12 July 2018
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
STING is a direct innate immune sensor of cyclic di-GMP
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
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12 July 2018
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
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12 July 2018
Transforming binding affinities from three dimensions to two with application to cadherin clustering
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12 July 2018
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
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12 July 2018
Immune signaling by RIG-I-like receptors
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12 July 2018
Structural biology of the Toll-like receptor family
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12 July 2018
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations
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12 July 2018
Structural insights into the assembly and activation of IL-1β with its receptors
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12 July 2018
The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain
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12 July 2018
Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I
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12 July 2018
Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes
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12 July 2018
Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
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PubMed Central
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12 July 2018
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
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PubMed Central
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12 July 2018
The IL-1 family: regulators of immunity
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12 July 2018
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
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PubMed Central
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12 July 2018
Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)
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12 July 2018
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling
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12 July 2018
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
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PubMed Central
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12 July 2018
Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors
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12 July 2018
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
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12 July 2018
The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress.
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12 July 2018
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structures of the toll-like receptor family and its ligand complexes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Interferon-inducible Ifi200-family genes in systemic lupus erythematosus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structures of TLR-ligand complexes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
retrieved
12 July 2018
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The NLR gene family: a standard nomenclature
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
retrieved
12 July 2018
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
retrieved
12 July 2018
VISA is an adapter protein required for virus-triggered IFN-beta signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The evolution of vertebrate Toll-like receptors
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Crystal structure of human toll-like receptor 3 (TLR3) ectodomain
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The bacterial flagellar motor: structure and function of a complex molecular machine
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structure and function of lipopolysaccharides.
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12 July 2018
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP)
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12 July 2018
Lipopolysaccharide endotoxins
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
The leucine-rich repeat as a protein recognition motif
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12 July 2018
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394028
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12 July 2018
Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region
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12 July 2018
The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness
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12 July 2018
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
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12 July 2018
The chemical structure of bacterial endotoxin in relation to bioactivity
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12 July 2018
Approaching the asymptote? Evolution and revolution in immunology
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12 July 2018
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells
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26 September 2018
The molecular structure of the TLR3 extracellular domain.
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26 September 2018
Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14.
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26 September 2018
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Crystal structure of CD14 and its implications for lipopolysaccharide signaling
1 reference
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PubMed
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1146/ANNUREV-IMMUNOL-032414-112258
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PMC publication ID
4394028
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PubMed publication ID
25622194
1 reference
stated in
Europe PubMed Central
PMC publication ID
4394028
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622194%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
ResearchGate publication ID
271533150
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