(Q35387923)

English

Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

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Europe PubMed Central

Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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author name string

Peter V Usatyuk

1

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Europe PubMed Central

PubMed publication ID

8 August 2017

Viswanathan Natarajan

2

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Europe PubMed Central

PubMed publication ID

8 August 2017

publication date

6 May 2011

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Europe PubMed Central

PubMed publication ID

8 August 2017

Microvascular Research

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Europe PubMed Central

PubMed publication ID

8 August 2017

83

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Europe PubMed Central

PubMed publication ID

8 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

45-55

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Europe PubMed Central

PubMed publication ID

8 August 2017

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

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Role of 4-hydroxy-trans-2-nonenal in cell functions

1 reference

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Pathological aspects of lipid peroxidation.

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Reactive species and mitochondrial dysfunction: mechanistic significance of 4-hydroxynonenal

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Generation and biological activities of oxidized phospholipids

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

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1 reference

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1 reference

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4-hydroxynonenal and cell cycle

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27 July 2018

Signaling mechanisms regulating endothelial permeability

1 reference

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Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase

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Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac.

1 reference

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Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases

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Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids

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Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity

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Role of 4-hydroxynonenal in stress-mediated apoptosis signaling

1 reference

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27 July 2018

Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis

1 reference

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Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling

1 reference

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27 July 2018

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

1 reference

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Focal adhesion kinase: the first ten years

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4-Hydroxynonenal impairs the permeability of an in vitro rat blood-brain barrier

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Cytoskeletal regulation of pulmonary vascular permeability

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27 July 2018

IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

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27 July 2018

4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications

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27 July 2018

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RhoA inactivation enhances endothelial barrier function

1 reference

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27 July 2018

4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis.

1 reference

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27 July 2018

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

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27 July 2018

Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.

1 reference

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27 July 2018

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27 July 2018

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.

1 reference

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27 July 2018

4-hydroxynonenal specifically inhibits c-myb but does not affect c-fos expressions in HL-60 cells

1 reference

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27 July 2018

Cytoskeletal modifications induced by 4-hydroxynonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

27 July 2018

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

27 July 2018

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

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27 July 2018

4-Hydroxy-2-nonenal induces calcium overload via the generation of reactive oxygen species in isolated rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

In vitro and in silico characterization of peroxiredoxin 6 modified by 4-hydroxynonenal and 4-oxononenal

1 reference

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26 September 2018

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

Endothelial cell regulation by phospholipid oxidation products

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26 September 2018

Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins.

1 reference

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26 September 2018

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26 September 2018

Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Structural characteristics of a lipid peroxidation product, trans-2-nonenal, that favour inhibition of membrane-associated phosphotyrosine phosphatase activity.

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26 September 2018

Formation of 4-hydroxy-2-nonenal protein adducts in the ischemic rat heart after transplantation

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26 September 2018

Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction

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26 September 2018

Susceptibility of actin to modification by 4-hydroxy-2-nonenal

1 reference

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26 September 2018

Signaling kinases modulated by 4-hydroxynonenal.

1 reference

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26 September 2018

p38 MAP kinase-dependent regulation of endothelial cell permeability

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26 September 2018

NF-kappaB activation mechanism of 4-hydroxyhexenal via NIK/IKK and p38 MAPK pathway

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26 September 2018

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26 September 2018

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26 September 2018

Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins

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26 September 2018

Role of mitogen-activated protein kinases in 4-hydroxy-2-nonenal-induced actin remodeling and barrier function in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Redox regulation of reactive oxygen species-induced p38 MAP kinase activation and barrier dysfunction in lung microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Reversible S-glutathionylation of Cys 374 regulates actin filament formation by inducing structural changes in the actin molecule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Aldehydes from n-6 fatty acid peroxidation. Effects on aminophospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Phospholipase D/phosphatidic acid signal transduction: role and physiological significance in lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of nonenzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Increased levels of 4-hydroxynonenal in human monocytes fed with malarial pigment hemozoin. A possible clue for hemozoin toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Cytoskeletal alterations in cultured cardiomyocytes following exposure to the lipid peroxidation product, 4-hydroxynonenal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Inhibition of c-myc expression induced by 4-hydroxynonenal, a product of lipid peroxidation, in the HL-60 human leukemic cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

26 September 2018

Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

24 October 2018

Actin Cys374 as a nucleophilic target of α,β-unsaturated aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

24 October 2018

Regulation of rat hepatocyte protein kinase C ? isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: A signaling pathway to modulate vesicular transport of glycoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196796

24 October 2018

4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for aldehydes bound to liver microsomal protein following CCl4 or BrCCl3 poisoning

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxynonenal, a metabolite of lipid peroxidation, activates phospholipase D in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative inactivation of human and sheep platelet membrane-associated phosphotyrosine phosphatase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel function of lecithin-cholesterol acyltransferase. Hydrolysis of oxidized polar phospholipids generated during lipoprotein oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatase inhibitors potentiate 4-hydroxynonenal-induced phospholipase D activation in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential involvement of 4-hydroxynonenal in the response of human lung cells to ozone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling of apoptotic lung injury by lipid hydroperoxides

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polar head groups are important for barrier-protective effects of oxidized phospholipids on pulmonary endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21570987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MVR.2011.04.012

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

release_gaaf22jjmja57drfdzeq47c5w4

1 reference

https://api.fatcat.wiki/v0/release/gaaf22jjmja57drfdzeq47c5w4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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