(Q35415906)

English

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1 (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kanokkarn Phromnoi

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Pornngarm Limtrakul

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Pornngarm Limtrakul

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Sahdeo Prasad

2

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9 February 2020

Subash C Gupta

3

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9 February 2020

Ramaswamy Kannappan

4

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9 February 2020

Simone Reuter

5

1 reference

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9 February 2020

Bharat B Aggarwal

8

1 reference

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9 February 2020

publication date

4 August 2011

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9 February 2020

Molecular Pharmacology

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

80

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

5

1 reference

Europe PubMed Central

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9 February 2020

889-899

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3

1 reference

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27 July 2018

Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways

1 reference

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27 July 2018

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

1 reference

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27 July 2018

STATs in cancer inflammation and immunity: a leading role for STAT3

1 reference

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27 July 2018

Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

STAT3-stathmin interactions control microtubule dynamics in migrating T-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis

1 reference

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27 July 2018

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Polymethoxylated flavones induce Ca(2+)-mediated apoptosis in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Proteasome inhibitor bortezomib for the treatment of multiple myeloma.

1 reference

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27 July 2018

A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma

1 reference

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27 July 2018

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Anti-HIV-1 cycloartanes from leaves and twigs of Gardenia thailandica

1 reference

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27 July 2018

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3',4'-pentamethoxyflavone (Sinensetin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Murine SHP-1 splice variants with altered Src homology 2 (SH2) domains. Implications for the SH2-mediated intramolecular regulation of SHP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

STATs: signal transducers and activators of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198920

27 July 2018

Antimicrobial activity of some medicinal species from the Dakar markets

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27 July 2018

Features of the anti-ulcer effects of Oren-gedoku-to (a traditional Chinese medicine) and its component herb drugs

1 reference

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27 July 2018

Simultaneous determination of five bioactive flavonoids in pericarpium Citri reticulatae from china by high-performance liquid chromatography with dual wavelength detection

1 reference

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26 September 2018

Flavones as colorectal cancer chemopreventive agents--phenol-o-methylation enhances efficacy.

1 reference

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26 September 2018

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1 reference

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26 September 2018

Human protein tyrosine phosphatase 1C (PTPN6) gene structure: alternate promoter usage and exon skipping generate multiple transcripts

1 reference

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26 September 2018

Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri

1 reference

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12 December 2020

based on heuristic

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Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.111.073676

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816954%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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9 February 2020

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