(Q35453850)

25843049

8 August 2017

title

Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines (English)

1 reference

8 August 2017

1 reference

Maria Cristina Nostro

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Andrew Elefanty

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Gordon M. Keller

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Farida Sarangi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Chaoxing Yang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Andrew Holland

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Edouard G Stanley

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Dale L Greiner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

2 April 2015

1 reference

8 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

591-604

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

Generation of functional human pancreatic β cells in vitro

8 June 2020

cites work

1 reference

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Generation of the epicardial lineage from human pluripotent stem cells

12 July 2018

1 reference

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Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

12 July 2018

1 reference

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Pancreas development in humans

12 July 2018

1 reference

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Development of the human pancreas from foregut to endocrine commitment.

12 July 2018

1 reference

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Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine

12 July 2018

1 reference

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Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice

12 July 2018

1 reference

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INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

12 July 2018

1 reference

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Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells

12 July 2018

1 reference

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Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Production of functional glucagon-secreting α-cells from human embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Dynamic signaling network for the specification of embryonic pancreas and liver progenitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Developmental biology of the pancreas: a comprehensive review

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

An illustrated review of early pancreas development in the mouse.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

EGF-ERBB signalling: towards the systems level

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Lack of TCF2/vHNF1 in mice leads to pancreas agenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Regulation of pancreas development by hedgehog signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Notochord repression of endodermal Sonic hedgehog permits pancreas development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes

12 July 2018

1 reference

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Transforming growth factor-alpha (TGF-alpha) and insulin gene expression in human fetal pancreas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Immunohistochemical detection of beta-galactosidase or green fluorescent protein on tissue sections

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

A multipotent progenitor domain guides pancreatic organogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Generation of insulin-producing islet-like clusters from human embryonic stem cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400642

Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25843049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25843049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25843049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEMCR.2015.02.017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

25843049

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25843049%20AND%20SRC:MED&resulttype=core&format=json