(Q35476091)

8 August 2017

title

Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death (English)

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8 August 2017

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9

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8 August 2017

V Ratushny

1

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8 August 2017

H B Pathak

2

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8 August 2017

N Beeharry

3

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8 August 2017

N Tikhmyanova

4

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8 August 2017

F Xiao

5

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8 August 2017

T Li

6

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8 August 2017

S Litwin

7

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8 August 2017

D C Connolly

8

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8 August 2017

L M Weiner

10

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8 August 2017

A K Godwin

11

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8 August 2017

E A Golemis

12

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8 August 2017

language of work or name

English

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publication date

25 July 2011

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8 August 2017

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8 August 2017

volume

31

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8 August 2017

issue

10

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8 August 2017

page(s)

1217-1227

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Aurora A kinase activity influences calcium signaling in kidney cells

8 August 2017

cites work

1 reference

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27 July 2018

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27 July 2018

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27 July 2018

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Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias

27 July 2018

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Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations

27 July 2018

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Src signaling in cancer invasion

27 July 2018

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27 July 2018

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27 July 2018

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Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib.

27 July 2018

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27 July 2018

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Src continues aging: current and future clinical directions.

27 July 2018

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Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells

27 July 2018

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Molecular targeted therapies and chemotherapy in malignant gliomas.

27 July 2018

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HEF1-dependent Aurora A activation induces disassembly of the primary cilium

27 July 2018

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Current role of antibody therapy in patients with metastatic colorectal cancer.

27 July 2018

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Therapeutic targets of multiple angiogenic factors for the treatment of cancer and metastasis

27 July 2018

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Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival

27 July 2018

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Genetic screening for signal transduction in the era of network biology

27 July 2018

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PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

27 July 2018

1 reference

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Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle

27 July 2018

1 reference

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Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

27 July 2018

1 reference

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The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

27 July 2018

1 reference

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Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

27 July 2018

1 reference

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Enforced adhesion of hematopoietic cells to culture dish induces endomitosis and polyploidy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Aurora kinases, aneuploidy and cancer, a coincidence or a real link?

27 July 2018

1 reference

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Aurora-kinase inhibitors as anticancer agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells

27 July 2018

1 reference

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27 July 2018

A renaissance for SRC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

27 July 2018

1 reference

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

27 July 2018

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Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

27 July 2018

1 reference

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On the role of aurora-A in centrosome function

27 July 2018

1 reference

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Meeting at mitosis: cell cycle-specific regulation of c-Src by RPTPalpha

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

27 July 2018

1 reference

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Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Autonomy of the epithelial phenotype in human ovarian surface epithelium: changes with neoplastic progression and with a family history of ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Multinucleation and inhibition of cytokinesis in suspended cells: reversal upon reattachment to a substrate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Movement of membrane domains and requirement of membrane signaling molecules for cytokinesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Meeting at Mitosis: Cell Cycle-Specific Regulation of c-Src by RPTP

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204164

Src Signaling Regulates Completion of Abscission in Cytokinesis through ERK/MAPK Activation at the Midbody

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2011.314

21 January 2018

Identifiers

DOI

10.1038/ONC.2011.314

1 reference

8 August 2017

1 reference

8 August 2017

1 reference