(Q35528327)

8 August 2017

title

Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation (English)

1 reference

8 August 2017

Rajeev Mishra

1

1 reference

8 August 2017

Takayoshi Watanabe

2

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8 August 2017

Makoto T Kimura

3

1 reference

8 August 2017

Nobuko Koshikawa

4

1 reference

8 August 2017

Maki Ikeda

5

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8 August 2017

Shota Uekusa

6

1 reference

8 August 2017

Hiroyuki Kawashima

7

1 reference

8 August 2017

Xiaofei Wang

8

1 reference

8 August 2017

Jun Igarashi

9

1 reference

8 August 2017

Diptiman Choudhury

10

1 reference

8 August 2017

Carla Grandori

11

1 reference

8 August 2017

Christopher J Kemp

12

1 reference

8 August 2017

Miki Ohira

13

1 reference

8 August 2017

Narendra K Verma

14

1 reference

8 August 2017

Yujin Kobayashi

15

1 reference

8 August 2017

Jin Takeuchi

16

1 reference

8 August 2017

Tsugumichi Koshinaga

17

1 reference

8 August 2017

Norimichi Nemoto

18

1 reference

8 August 2017

Noboru Fukuda

19

1 reference

8 August 2017

Masayoshi Soma

20

1 reference

8 August 2017

Takeshi Kusafuka

21

1 reference

8 August 2017

Kyoko Fujiwara

22

1 reference

8 August 2017

Hiroki Nagase

23

1 reference

8 August 2017

publication date

3 March 2015

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8 August 2017

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8 August 2017

volume

106

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8 August 2017

issue

4

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8 August 2017

page(s)

421-429

1 reference

Inhibition of malignant phenotypes of human osteosarcoma cells by a gene silencer, a pyrrole-imidazole polyamide, which targets an E-box motif

8 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Activity of a Py-Im polyamide targeted to the estrogen response element

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Antitumor activity of a pyrrole-imidazole polyamide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

MYC in oncogenesis and as a target for cancer therapies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Over-expression of eukaryotic translation initiation factor 4 gamma 1 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Pretranscriptional regulation of Tgf-beta1 by PI polyamide prevents scarring and accelerates wound healing of the cornea after exposure to alkali

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

DNA sequence selectivity of hairpin polyamide turn units

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Global regulation of nucleotide biosynthetic genes by c-Myc

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

c-Myc and eIF4F are components of a feedforward loop that links transcription and translation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Improved low molecular weight Myc-Max inhibitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

The c-Myc target gene network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Myc-binding-site recognition in the human genome is determined by chromatin context

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Programmable DNA binding oligomers for control of transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Transcriptional regulation and transformation by Myc proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Arresting cancer proliferation by small-molecule gene regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Low molecular weight inhibitors of Myc-Max interaction and function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Genomic targets of the human c-Myc protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Function and regulation of the transcription factors of the Myc/Max/Mad network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Identification of CDK4 as a target of c-MYC.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-beta 1-mediated growth inhibition in EBV-positive B cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406810

Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5.

12 July 2018

1 reference

Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter.

21 January 2018

1 reference

A pyrrole-imidazole polyamide targeting transforming growth factor-beta1 inhibits restenosis and preserves endothelialization in the injured artery

21 January 2018

1 reference

Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CAS.12610

1 reference

8 August 2017

1 reference

8 August 2017

1 reference