(Q35529695)

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Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models

scientific article published on 25 February 2015

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Europe PubMed Central

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1 March 2020

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models (English)

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1 March 2020

Parkinson's disease

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Jau-Shyong Hong

10

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1 March 2020

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Qingshan Wang

1

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1 March 2020

Li Qian

2

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1 March 2020

Shih-Heng Chen

3

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1 March 2020

Chun-Hsien Chu

4

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1 March 2020

Belinda Wilson

5

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1 March 2020

Esteban Oyarzabal

6

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1 March 2020

Syed Ali

7

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1 March 2020

Bonnie Robinson

8

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1 March 2020

Deepa Rao

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1 March 2020

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25 February 2015

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1 March 2020

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1 March 2020

138

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1 March 2020

Pt 5

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1 March 2020

1247-1262

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1 March 2020

Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase

1 reference

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Subsite awareness in neuropathology evaluation of National Toxicology Program (NTP) studies: a review of select neuroanatomical structures with their functional significance in rodents

1 reference

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NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

1 reference

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1 reference

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NADPH oxidases: novel therapeutic targets for neurodegenerative diseases

1 reference

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HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.

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Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

1 reference

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Neurotoxic in vivo models of Parkinson's disease recent advances.

1 reference

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27 July 2018

Microglia in neurodegenerative disease

1 reference

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27 July 2018

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

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Classical inhibitors of NOX NAD(P)H oxidases are not specific.

1 reference

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27 July 2018

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

1 reference

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Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

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27 July 2018

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

1 reference

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27 July 2018

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

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27 July 2018

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

1 reference

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NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies

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27 July 2018

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

1 reference

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NOX enzymes and the biology of reactive oxygen

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27 July 2018

Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase

1 reference

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Microglial response to brain injury: a brief synopsis

1 reference

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27 July 2018

Do compensatory processes underlie the preclinical phase of neurodegenerative disease? Insights from an animal model of parkinsonism

1 reference

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27 July 2018

Suppression of inflammatory arthritis by simultaneous inhibition of nitric oxide synthase and NADPH oxidase.

1 reference

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Compensations after lesions of central dopaminergic neurons: some clinical and basic implications

1 reference

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27 July 2018

Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases

1 reference

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26 September 2018

Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems

1 reference

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The immunology of neurodegeneration

1 reference

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26 September 2018

Neurodegeneration and inflammation in Parkinson's disease

1 reference

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Current management of Parkinson's disease

1 reference

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26 September 2018

Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease

1 reference

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26 September 2018

Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity.

1 reference

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NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies

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Neuroprotection trials in Parkinson's disease: systematic review

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NOX enzymes as novel targets for drug development

1 reference

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How to improve neuroprotection in Parkinson's disease?

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Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

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Some aspects of the pharmacology of diphenyleneiodonium, a bivalent iodine compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/25716193

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of reactive O2 in phagocyte-induced hypermetabolism and pulmonary injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25716193

12 December 2020

based on heuristic

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10.1093/BRAIN/AWV034

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Europe PubMed Central

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1 March 2020

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Europe PubMed Central

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1 March 2020

PubMed publication ID

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1 March 2020

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