(Q35533133)

8 August 2017

title

Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice (English)

1 reference

8 August 2017

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1 reference

Sharon Manley

5

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author name string

Hong-Min Ni

1

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8 August 2017

Amar Bhakta

2

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8 August 2017

Shaogui Wang

3

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8 August 2017

Zhenrui Li

4

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8 August 2017

Heqing Huang

6

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8 August 2017

Bryan Copple

7

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8 August 2017

Wen-Xing Ding

8

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8 August 2017

language of work or name

English

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publication date

23 December 2014

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8 August 2017

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8 August 2017

volume

9

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8 August 2017

issue

12

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8 August 2017

page(s)

e115849

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Creative Commons Attribution 4.0 International

8 August 2017

copyright license

start time

23 December 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4275262/fullTextXML

inferred from PubMed Central ID database lookup

cites work

New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Activation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal gland

12 July 2018

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Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

12 July 2018

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Animals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: pathophysiology, translational relevance, and challenges

12 July 2018

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Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy

12 July 2018

1 reference

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Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver

12 July 2018

1 reference

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Hepatitis C and alcohol exacerbate liver injury by suppression of FOXO3.

12 July 2018

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Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity

12 July 2018

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Regulation of FOXO3 by phosphorylation and methylation in hepatitis C virus infection and alcohol exposure

12 July 2018

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Forkhead box class O transcription factors in liver function and disease

12 July 2018

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Functions of autophagy in normal and diseased liver

12 July 2018

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Mouse model of chronic and binge ethanol feeding (the NIAAA model)

12 July 2018

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Guidelines for the use and interpretation of assays for monitoring autophagy

12 July 2018

1 reference

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Autophagy in alcohol-induced liver diseases

12 July 2018

1 reference

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Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury

12 July 2018

1 reference

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Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis

12 July 2018

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Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Alcoholic liver disease: pathogenesis and new therapeutic targets

12 July 2018

1 reference

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Selective taste of ethanol-induced autophagy for mitochondria and lipid droplets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

12 July 2018

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Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice.

12 July 2018

1 reference

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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Hypoxia-induced autophagy: cell death or cell survival?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Regulation of autophagy through multiple independent hypoxic signaling pathways.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Autophagy regulates lipid metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

FOXO-binding partners: it takes two to tango

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

FoxO3 controls autophagy in skeletal muscle in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

The role of hypoxia in vascular injury and repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

The lipin protein family: dual roles in lipid biosynthesis and gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1alpha

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Impaired mitochondrial function in microvesicular steatosis. Effects of drugs, ethanol, hormones and cytokines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

Hypoxia-induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia-tolerant mole rat, Spalax ehrenbergi.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4275262

HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice

26 September 2018

1 reference

12 December 2020

HIF-1α is a major and complex player in alcohol induced liver diseases

1 reference

12 December 2020

Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo

1 reference

12 December 2020

Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients

1 reference

12 December 2020

Chronic ethanol and triglyceride turnover in white adipose tissue in rats: inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0115849

Identifiers

DOI

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8 August 2017

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8 August 2017

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