(Q35535315)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Lead optimization of antimalarial propafenone analogues (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Dennis E Kyle

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

R. Kiplin Guy

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

17

Jon Mirsalis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

9

W Armand Guiguemde

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Andrew Lemoff

8

0 references

Michele C Connelly

14

object named as

Michele C Connelly

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

6

Fangyi Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

15

Joseph L Derisi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

10

Martina Sigal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

3

Lalitha V Iyer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

7

Anna Furimsky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

5

Jason Gow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

4

Toufan Parman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

David Lowes

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Julie A Clark

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Emily Wilson

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Liang Tang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

29 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

6087-6093

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

A major genome region underlying artemisinin resistance in malaria

5 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Optimization of propafenone analogues as antimalarial leads

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Artemisinin resistance: current status and scenarios for containment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Artemisinin Resistance in Plasmodium falciparum Malaria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Dual detection approach to a more accurate measure of relative purity in high-throughput characterization of compound collections

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Searching for new antimalarial therapeutics amongst known drugs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Drug resistance hampers our capacity to roll back malaria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Inhibition of cytochrome P450 2D6: structure-activity studies using a series of quinidine and quinine analogues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Identification and determination of phase I metabolites of propafenone in rat liver perfusate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Relations among antimalarial drugs: results of studies with cycloguanil-, sulfone-, or chloroquine-resistant Plasmodium berghei in mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Human malaria parasites in continuous culture. 1976.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4408918

26 September 2018

Identifiers

DOI

10.1021/JM300286A

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

22708838

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22708838%20AND%20SRC:MED&resulttype=core&format=json