(Q35546447)

English

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.

scientific article published on 21 January 2015

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scholarly article

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28 February 2020

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands (English)

1 reference

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28 February 2020

Manuel Iglesias-Bexiga

1

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28 February 2020

Francisco Castillo

2

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28 February 2020

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28 February 2020

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Eva S Cobos

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28 February 2020

Tsutomu Oka

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28 February 2020

Marius Sudol

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28 February 2020

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21 January 2015

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28 February 2020

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28 February 2020

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28 February 2020

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28 February 2020

e0113828

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28 February 2020

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Creative Commons Attribution 4.0 International

21 January 2015

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April 2022 Public Data File from Crossref

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0 references

Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene

1 reference

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1 reference

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1 reference

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1 reference

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Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome

1 reference

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1 reference

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A Smad action turnover switch operated by WW domain readers of a phosphoserine code

1 reference

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Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway

1 reference

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Computational design and experimental testing of the fastest-folding β-sheet protein

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Atomic-level characterization of the structural dynamics of proteins

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12 July 2018

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

1 reference

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12 July 2018

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

1 reference

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12 July 2018

Modularity in the Hippo signaling pathway

1 reference

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12 July 2018

The Hippo pathway regulates Wnt/beta-catenin signaling

1 reference

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12 July 2018

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

1 reference

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A thermodynamic approach to the affinity optimization of drug candidates

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Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions

1 reference

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CHARMM: the biomolecular simulation program

1 reference

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12 July 2018

Do enthalpy and entropy distinguish first in class from best in class?

1 reference

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12 July 2018

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

12 July 2018

Structural characterisation of PinA WW domain and a comparison with other group IV WW domains, Pin1 and Ess1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

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The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity

1 reference

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12 July 2018

YAP1 increases organ size and expands undifferentiated progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

12 July 2018

Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

12 July 2018

Identifying specificity profiles for peptide recognition modules from phage-displayed peptide libraries

1 reference

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12 July 2018

PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations

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12 July 2018

Hippo signaling in organ size control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

12 July 2018

NMR structural studies of the ItchWW3 domain reveal that phosphorylation at T30 inhibits the interaction with PPxY-containing ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301871

12 July 2018

WW or WoW: the WW domains in a union of bliss

1 reference

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Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction

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Comparative structural and energetic analysis of WW domain-peptide interactions

1 reference

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Thermodynamics of binding to SH3 domains: the energetic impact of polyproline II (PII) helix formation

1 reference

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Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design

1 reference

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WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

1 reference

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WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

1 reference

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Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope

1 reference

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The role of backbone motions in ligand binding to the c-Src SH3 domain

1 reference

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Solution structure of a Nedd4 WW domain-ENaC peptide complex

1 reference

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Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities

1 reference

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Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR.

1 reference

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Phage display for selection of novel binding peptides

1 reference

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Searching for specificity in SH domains

1 reference

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1 reference

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Using molecular repertoires to identify high-affinity peptide ligands of the WW domain of human and mouse YAP.

1 reference

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1 reference

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Evaluation of comparative protein modeling by MODELLER

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The WW domain: a signalling site in dystrophin?

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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21 January 2018

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1 reference

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21 January 2018

Heat capacity of proteins. II. Partial molar heat capacity of the unfolded polypeptide chain of proteins: protein unfolding effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25607641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Converging on proline: the mechanism of WW domain peptide recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/25607641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heat capacity of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/25607641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WW domains in the heart of Smad regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25607641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0113828

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25607641%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

2015PLoSO..1013828I

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25607641%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25607641%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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