(Q35549078)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

11

1 reference

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5 March 2020

Serene W Chen

1

1 reference

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5 March 2020

Francesco Antonio Aprile

5

1 reference

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5 March 2020

Cintia Roodveldt

8

1 reference

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5 March 2020

Nicholas W. Wood

12

1 reference

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5 March 2020

Tuomas Knowles

13

1 reference

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5 March 2020

Carlos Alfonso

14

1 reference

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5 March 2020

German Rivas

15

1 reference

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5 March 2020

Andrey Y. Abramov

16

1 reference

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5 March 2020

José María Valpuesta

17

1 reference

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5 March 2020

Nunilo Cremades

19

1 reference

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5 March 2020

18

Christopher M Dobson

1 reference

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5 March 2020

10

Erwin J De-Genst

1 reference

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5 March 2020

author name string

Srdja Drakulic

2

1 reference

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5 March 2020

Emma Deas

3

1 reference

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5 March 2020

Myriam Ouberai

4

1 reference

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5 March 2020

Rocío Arranz

6

1 reference

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5 March 2020

Samuel Ness

7

1 reference

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5 March 2020

Tim Guilliams

9

1 reference

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5 March 2020

language of work or name

English

0 references

publication date

8 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

5 March 2020

published in

1 reference

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5 March 2020

volume

112

1 reference

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5 March 2020

page(s)

E1994-2003

1 reference

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5 March 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

Structural insights into amyloid oligomers of the Parkinson disease-related protein α-synuclein.

5 March 2020

cites work

1 reference

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The amyloid state and its association with protein misfolding diseases.

27 July 2018

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The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

27 July 2018

1 reference

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In vitro study of α-synuclein protofibrils by cryo-EM suggests a Cu(2+)-dependent aggregation pathway

27 July 2018

1 reference

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α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling

27 July 2018

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Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation

27 July 2018

1 reference

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Mechanism of oxidative stress in neurodegeneration

27 July 2018

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Direct observation of the interconversion of normal and toxic forms of α-synuclein

27 July 2018

1 reference

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Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships

27 July 2018

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The amyloid state of proteins in human diseases

27 July 2018

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Atomic View of a Toxic Amyloid Small Oligomer

27 July 2018

1 reference

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Antiparallel -sheet architecture in Iowa-mutant -amyloid fibrils

27 July 2018

1 reference

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Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM

27 July 2018

1 reference

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Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

27 July 2018

1 reference

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

27 July 2018

1 reference

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Molecular mechanisms of nitrosative stress-mediated protein misfolding in neurodegenerative diseases

27 July 2018

1 reference

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Protein misfolding, functional amyloid, and human disease

27 July 2018

1 reference

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Amyloid ion channels: a common structural link for protein-misfolding disease

27 July 2018

1 reference

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Metals, toxicity and oxidative stress

27 July 2018

1 reference

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Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress

27 July 2018

1 reference

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Protein folding and misfolding

27 July 2018

1 reference

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

27 July 2018

1 reference

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

27 July 2018

1 reference

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

27 July 2018

1 reference

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

27 July 2018

1 reference

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Biochemical characterization of the core structure of alpha-synuclein filaments

27 July 2018

1 reference

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Understanding protein folding via free-energy surfaces from theory and experiment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

27 July 2018

1 reference

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EMAN: semiautomated software for high-resolution single-particle reconstructions

27 July 2018

1 reference

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Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing

27 July 2018

1 reference

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

27 July 2018

1 reference

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Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

27 July 2018

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Lipids of nervous tissue: composition and metabolism

27 July 2018

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Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

27 July 2018

1 reference

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High stability and cooperative unfolding of α-synuclein oligomers

26 September 2018

1 reference

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Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity

26 September 2018

1 reference

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Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry.

26 September 2018

1 reference

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The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

26 September 2018

1 reference

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Atomic structure and hierarchical assembly of a cross- amyloid fibril

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Lipid bilayer disruption by oligomeric alpha-synuclein depends on bilayer charge and accessibility of the hydrophobic core.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Conformational plasticity of the Gerstmann-Sträussler-Scheinker disease peptide as indicated by its multiple aggregation pathways

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

The fold of alpha-synuclein fibrils

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Early stages of misfolding and association of beta2-microglobulin: insights from infrared spectroscopy and dynamic light scattering.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Molecular mechanism of antimicrobial peptides: the origin of cooperativity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein

26 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

Structural properties of pore-forming oligomers of alpha-synuclein

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413268

26 September 2018

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

Examination of the Structure of the Transthyretin Amyloid Fibril by Image Reconstruction from Electron Micrographs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

The protofilament substructure of amyloid fibrils11Edited by F. E. Cohen

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

Xmipp: An Image Processing Package for Electron Microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

HYDROMIC: prediction of hydrodynamic properties of rigid macromolecular structures obtained from electron microscopy images

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1421204112

Study of vesicle leakage induced by melittin

21 January 2018

1 reference

12 December 2020

Differing molecular mechanisms appear to underlie early toxicity of prefibrillar HypF-N aggregates to different cell types

1 reference

12 December 2020

Parallel β-sheet fibril and antiparallel β-sheet oligomer: new insights into amyloid formation of hen egg white lysozyme under heat and acidic condition from FTIR spectroscopy

1 reference

12 December 2020

The presence of an air-water interface affects formation and elongation of α-Synuclein fibrils

1 reference

12 December 2020

The mode of α-synuclein binding to membranes depends on lipid composition and lipid to protein ratio

1 reference

12 December 2020

Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching

1 reference

12 December 2020

Determination of the sedimentation coefficient distribution by least-squares boundary modeling

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1421204112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

0 references

release_u24juc7gprbyxl2t2yke76emn4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u24juc7gprbyxl2t2yke76emn4

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855634%20AND%20SRC:MED&resulttype=core&format=json