(Q35552324)

8 August 2017

title

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation (English)

1 reference

8 August 2017

Katherine R Mattaini

1

1 reference

8 August 2017

Edward J Brignole

2

1 reference

8 August 2017

Mitali Kini

3

1 reference

8 August 2017

Shawn M Davidson

4

1 reference

8 August 2017

Brian P Fiske

5

1 reference

8 August 2017

Catherine L Drennan

6

1 reference

8 August 2017

Matthew G Vander Heiden

7

1 reference

8 August 2017

publication date

29 April 2015

1 reference

8 August 2017

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8 August 2017

volume

3

1 reference

8 August 2017

page(s)

5

1 reference

Creative Commons Attribution 4.0 International

8 August 2017

copyright license

start time

29 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4414297/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth

12 July 2018

1 reference

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The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation

12 July 2018

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Serine, glycine and one-carbon units: cancer metabolism in full circle

12 July 2018

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

12 July 2018

1 reference

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Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

12 July 2018

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Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy

12 July 2018

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Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis

12 July 2018

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Contrasting catalytic and allosteric mechanisms for phosphoglycerate dehydrogenases

12 July 2018

1 reference

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PHGDH amplification and altered glucose metabolism in human melanoma

12 July 2018

1 reference

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Targeting cancer metabolism: a therapeutic window opens

12 July 2018

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

12 July 2018

1 reference

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

12 July 2018

1 reference

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Novel mutations in 3-phosphoglycerate dehydrogenase (PHGDH) are distributed throughout the protein and result in altered enzyme kinetics

12 July 2018

1 reference

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EMAN2: an extensible image processing suite for electron microscopy

12 July 2018

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D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberculosis is a link between the Escherichia coli and mammalian enzymes

12 July 2018

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Accurate determination of local defocus and specimen tilt in electron microscopy

12 July 2018

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Expression profiling reveals off-target gene regulation by RNAi

12 July 2018

1 reference

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The contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase

12 July 2018

1 reference

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Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenase

12 July 2018

1 reference

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SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

12 July 2018

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The mechanism of velocity modulated allosteric regulation in D-3-phosphoglycerate dehydrogenase. Cross-linking adjacent regulatory domains with engineered disulfides mimics effector binding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Enzymes of serine metabolism in normal, developing and neoplastic rat tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Enzymic imbalance in serine metabolism in human colon carcinoma and rat sarcoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Biomimetic-dye affinity adsorbents for enzyme purification: application to the one-step purification of Candida boidinii formate dehydrogenase.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Vmax regulation through domain and subunit changes. The active form of phosphoglycerate dehydrogenase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Crystal structure of Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase: extreme asymmetry in a tetramer of identical subunits

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Purification and subunit structure of phosphoglycerate dehydrogenase from rabbit liver

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414297

Genetic Approach to Facilitate Purification of Recombinant Proteins with a Novel Metal Chelate Adsorbent

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS40170-015-0131-7

D-3-Phosphoglycerate dehydrogenase from chicken liver. II. Chemical and physical properties

21 January 2018

1 reference

12 December 2020

Affinity chromatography of phosphofructokinase using Cibacron blue F3G-A

1 reference

12 December 2020

Location of proteins S5, S13 and S14 on the surface of the 3oS ribosomal subunit from Escherichia coli as determined by immune electron microscopy

1 reference

12 December 2020

Role of the transcription factor ATF4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids

1 reference

12 December 2020

Purification of muscle enzymes by pseudoaffinity chromatography

1 reference

12 December 2020

10.1186/S40170-015-0131-7

Identifiers

DOI

1 reference

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference