(Q35554899)

8 August 2017

1 reference

title

Metallothionein: a multifunctional protein from toxicity to cancer (English)

1 reference

8 August 2017

Metallothionein: A Multifunctional Protein from Toxicity to Cancer (English)

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

19 March 2024

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

19 March 2024

author name string

S. E. Theocharis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535585

19 March 2024

A. P. Margeli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535585

19 March 2024

A. Koutselinis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535585

19 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14535585

19 March 2024

publication date

1 July 2003

1 reference

The International Journal of Biological Markers

8 August 2017

1 reference

8 August 2017

18

1 reference

8 August 2017

3

1 reference

8 August 2017

162-169

1 reference

A CADMIUM PROTEIN FROM EQUINE KIDNEY CORTEX

8 August 2017

1

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

19 March 2024

2

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

CTG triplet repeat in mouse growth inhibitory factor/metallothionein III gene promoter represses the transcriptional activity of the heterologous promoters.

19 March 2024

3

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

MT-III, a brain-specific member of the metallothionein gene family

19 March 2024

4

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

19 March 2024

5

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Expression of the gene encoding metallothionein-3 in organs of the reproductive system

19 March 2024

7

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Bioactivity of Metallothionein-3 Correlates with Its Novel .beta. Domain Sequence Rather Than Metal Binding Properties

19 March 2024

8

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

2 Definitions and nomenclature of metallothioneins

19 March 2024

9

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein in physiological and physiopathological processes

19 March 2024

10

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

The glutathione redox couple modulates zinc transfer from metallothionein to zinc-depleted sorbitol dehydrogenase

19 March 2024

11

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Basal metallothionein in tumors: widespread presence of apoprotein

19 March 2024

12

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Biological significance of non-acetylated metallothionein

19 March 2024

13

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Zinc transfer from transcription factor IIIA fingers to thionein clusters

19 March 2024

14

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Sp1.

19 March 2024

15

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Inhibitory sites in enzymes: zinc removal and reactivation by thionein

19 March 2024

16

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein

19 March 2024

18

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Redox sensor function of metallothioneins

19 March 2024

19

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Selenium redox biochemistry of zinc-sulfur coordination sites in proteins and enzymes

19 March 2024

20

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein.

19 March 2024

21

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

A murine model of Menkes disease reveals a physiological function of metallothionein

19 March 2024

22

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Nitric oxide selectively releases metals from the amino-terminal domain of metallothioneins: potential role at inflammatory sites

19 March 2024

23

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Evidence supporting zinc as an important antioxidant for skin

19 March 2024

24

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide

19 March 2024

25

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

19 March 2024

26

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genes

19 March 2024

27

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

American Journal of Physiology

19 March 2024

28

273

L856

Pitt B.R.

1997

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity

19 March 2024

30

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs.

19 March 2024

31

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Reaction of a platinum(IV) complex with native Cd,Zn-metallothionein in vitro.

19 March 2024

32

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Interaction of sodium chloroplatinate and iproplatin with metallothionein in vivo

19 March 2024

33

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Specific induction of metallothionein synthesis by mitochondrial oxidative stress

19 March 2024

34

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Significance of metallothionein overexpression in human tumours

19 March 2024

35

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Possible chemoresistance-related genes for gastric cancer detected by cDNA microarray

19 March 2024

36

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability

19 March 2024

37

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms

19 March 2024

38

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

19 March 2024

39

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Divalent metal ions induce conformational change in pure, human wild-type p53 tumor suppressor protein

19 March 2024

40

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

19 March 2024

42

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Role of cysteine residues in regulation of p53 function

19 March 2024

43

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells

19 March 2024

44

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation

19 March 2024

46

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma

19 March 2024

47

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Enhanced apoptosis in metallothionein null cells

19 March 2024

48

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Role of metallothionein in carcinogenesis

19 March 2024

49

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Influence of metallothionein-1 localization on its function

19 March 2024

50

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing cardiomyocytes

19 March 2024

51

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein and apoptosis during differentiation of myoblasts to myotubes: protection against free radical toxicity.

19 March 2024

52

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines

19 March 2024

54

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Covalent sequestration of melphalan by metallothionein and selective alkylation of cysteines

19 March 2024

55

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Cellular and Molecular Biology

19 March 2024

56

46

383

He T.

2000

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein-mediated resistance to multiple drugs can be induced by several anticancer drugs in mice

19 March 2024

58

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: a specific gene therapy strategy

19 March 2024

59

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein Is a Potential Negative Regulator of Apoptosis

19 March 2024

60

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Metallothionein in radiation exposure: its induction and protective role

19 March 2024

61

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

The effect of cold stress on UVB injury in mouse skin and cultured keratinocytes

19 March 2024

62

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Photoprotective role of metallothionein in UV-injury - metallothionein-null mouse exhibits reduced tolerance against ultraviolet-B.

19 March 2024

63

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Novel function of metallothionein in photoprotection: metallothionein-null mouse exhibits reduced tolerance against ultraviolet B injury in the skin

19 March 2024

64

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

Induction of metallothionein synthesis in transplanted murine tumors by X irradiation

19 March 2024

65

1 reference

https://api.crossref.org/works/10.1177/172460080301800302

19 March 2024

Identifiers

10.5301/JBM.2008.196

1 reference

8 August 2017

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14535585

19 March 2024

1 reference