(Q35556010)

8 August 2017

title

Role of water in protein aggregation and amyloid polymorphism (English)

1 reference

8 August 2017

1 reference

1

D Thirumalai

1 reference

8 August 2017

Govardhan Reddy

2

1 reference

8 August 2017

John E Straub

series ordinal

3

1 reference

8 August 2017

publication date

15 July 2011

1 reference

Accounts of Chemical Research

8 August 2017

published in

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8 August 2017

volume

45

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8 August 2017

issue

1

1 reference

8 August 2017

page(s)

83-92

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Toward a molecular theory of early and late events in monomer to amyloid fibril formation

8 August 2017

cites work

1 reference

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Dry amyloid fibril assembly in a yeast prion peptide is mediated by long-lived structures containing water wires

27 July 2018

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Atomic-level characterization of the ensemble of the Aβ(1-42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms

27 July 2018

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Net charge per residue modulates conformational ensembles of intrinsically disordered proteins

27 July 2018

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Direct observation of nucleation and growth in amyloid self-assembly

27 July 2018

1 reference

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2D IR provides evidence for mobile water molecules in beta-amyloid fibrils

27 July 2018

1 reference

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Dynamics of locking of peptides onto growing amyloid fibrils

27 July 2018

1 reference

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Functional amyloids as natural storage of peptide hormones in pituitary secretory granules

27 July 2018

1 reference

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Effect of beta-sheet propensity on peptide aggregation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

What determines the structure and stability of KFFE monomers, dimers, and protofibrils?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Effect of dehydration on the aggregation kinetics of two amyloid peptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Influence of preformed Asp23-Lys28 salt bridge on the conformational fluctuations of monomers and dimers of Abeta peptides with implications for rates of fibril formation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Probing the mechanisms of fibril formation using lattice models

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Interactions between amino acid side chains in cylindrical hydrophobic nanopores with applications to peptide stability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Atomistic simulations of the effects of polyglutamine chain length and solvent quality on conformational equilibria and spontaneous homodimerization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Role of water in mediating the assembly of Alzheimer amyloid-beta Abeta16-22 protofilaments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

The structural basis of yeast prion strain variants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Monomer adds to preformed structured oligomers of Abeta-peptides by a two-stage dock-lock mechanism.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Structural insights into a yeast prion illuminate nucleation and strain diversity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Probing the instabilities in the dynamics of helical fragments from mouse PrPC.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Polymerization-depolymerization of tobacco mosaic virus protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Emerging ideas on the molecular basis of protein and peptide aggregation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Exploring the propensities of helices in PrP(C) to form beta sheet using NMR structures and sequence alignments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Amyloid fibers are water-filled nanotubes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Nucleated conformational conversion and the replication of conformational information by a prion determinant

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Dominant forces in protein folding

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Principles governing oligomer formation in amyloidogenic peptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Characterization of the nucleation barriers for protein aggregation and amyloid formation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Role of backbone-solvent interactions in determining conformational equilibria of intrinsically disordered proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Hydrophobic and ionic interactions in nanosized water droplets.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Atomic-level description of amyloid beta-dimer formation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

POLYMERIZATION-DEPOLYMERIZATION OF TOBACCO MOSAIC VIRUS PROTEIN. IV. THE ROLE OF WATER.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Dissecting the assembly of Abeta16-22 amyloid peptides into antiparallel beta sheets.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Pathway complexity of prion protein assembly into amyloid

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Energy landscape theory for Alzheimer's amyloid beta-peptide fibril elongation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Polymerization-depolymerization of tobacco mosaic virus protein. XII. Further studies on the role of water

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Dynamics of Asp23-Lys28 salt-bridge formation in Abeta10-35 monomers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Insights into the amyloid folding problem from solid-state NMR

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Factors Governing Fibrillogenesis of Polypeptide Chains Revealed by Lattice Models

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Beyond the prion principle

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218239

Amyloid fibril polymorphism is under kinetic control

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21761818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhancement of Protein Crystal Nucleation by Critical Density Fluctuations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21761818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interpreting the aggregation kinetics of amyloid peptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21761818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/AR2000869

1 reference

8 August 2017

1 reference

1 reference

8 August 2017

1 reference