(Q35557423)

8 August 2017

1 reference

title

In silico prediction of blood-brain barrier permeation (English)

1 reference

8 August 2017

In silico prediction of blood–brain barrier permeation (English)

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(03)02827-7

20 March 2024

1 reference

modelling biological systems

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14554156

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(03)02827-7

20 March 2024

1 reference

David E. Clark

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14554156

20 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14554156

20 March 2024

publication date

1 October 2003

1 reference

8 August 2017

15 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14554156

full work available at URL

20 March 2024

https://api.elsevier.com/content/article/PII:S1359644603028277?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(03)02827-7

https://api.elsevier.com/content/article/PII:S1359644603028277?httpAccept=text/plain

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1359-6446(03)02827-7

20 March 2024

1 reference

8 August 2017

volume

8

1 reference

8 August 2017

issue

20

1 reference

8 August 2017

page(s)

927-933

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Role of the development scientist in compound lead selection and optimization

8 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Drug and gene targeting to the brain with molecular Trojan horses

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Transporter-mediated permeation of drugs across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood-brain barrier in the pharmaceutical industry--background and current status in the drug discovery process.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Molecular factors influencing drug transfer across the blood-brain barrier.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Correlation and prediction of a large blood-brain distribution data set--an LFER study

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Computational approaches to the prediction of the blood-brain distribution

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Prediction of intestinal absorption and blood-brain barrier penetration by computational methods

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs

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7 January 2021

Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

A method to determine the ability of drugs to diffuse through the blood-brain barrier

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Designing libraries with CNS activity

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Predicting blood-brain barrier permeation from three-dimensional molecular structure.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

A neural network based virtual high throughput screening test for the prediction of CNS activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Predicting CNS permeability of drug molecules: comparison of neural network and support vector machine algorithms.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Prediction of CNS activity of compound libraries using substructure analysis

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7 January 2021

Prediction of blood-brain partitioning using Monte Carlo simulations of molecules in water

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7 January 2021

A simple model to predict blood-brain barrier permeation from 3D molecular fields

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Modeling blood-brain barrier partitioning using the electrotopological state.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Predicting blood-brain barrier partitioning of organic molecules using membrane-interaction QSAR analysis

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Recent advances in the prediction of blood-brain partitioning from molecular structure.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Blood-brain barrier permeation: molecular parameters governing passive diffusion

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Partitioning of ionizing molecules between aqueous buffers and phospholipid vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Molecular properties that influence the oral bioavailability of drug candidates

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Delivery of imaging agents into brain

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https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Dedicated small animal scanners: a new tool for drug development?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Assessment of blood-brain barrier penetration: in silico, in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2803%2902827-7

7 January 2021

Identifiers

1 reference

8 August 2017

1 reference