(Q35560382)

8 August 2017

1 reference

title

Role of mTOR signalling in the control of translation initiation and elongation by nutrients (English)

1 reference

8 August 2017

Role of mTOR Signalling in the Control of Translation Initiation and Elongation by Nutrients (English)

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_13

21 March 2024

author name string

C. G. Proud

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560960

21 March 2024

language of work or name

1 reference

1 January 2004

1 reference

full work available at URL

8 August 2017

http://link.springer.com/content/pdf/10.1007/978-3-642-18930-2_13.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_13

Current Topics in Microbiology and Immunology

21 March 2024

published in

1 reference

8 August 2017

volume

279

1 reference

8 August 2017

page(s)

215-244

1 reference

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

8 August 2017

cites work

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Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

21 March 2024

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Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.

21 March 2024

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Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation

21 March 2024

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Oral administration of leucine stimulates ribosomal protein mRNA translation but not global rates of protein synthesis in the liver of rats

21 March 2024

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Glucose depletion rapidly inhibits translation initiation in yeast

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The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.

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Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle

21 March 2024

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Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

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Intracellular signalling: PDK1--a kinase at the hub of things

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Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

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Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

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Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

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AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

21 March 2024

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Nutrients differentially regulate multiple translation factors and their control by insulin

21 March 2024

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Functional properties of phosphorylated elongation factor 2

21 March 2024

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Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

21 March 2024

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Site-specific conformational determination in thermal unfolding studies of helical peptides using vibrational circular dichroism with isotopic substitution

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Mammalian TOR: a homeostatic ATP sensor

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Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases

21 March 2024

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Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes

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Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain

21 March 2024

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A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E

21 March 2024

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Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

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Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes

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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 March 2024

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 March 2024

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Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

21 March 2024

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The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites

21 March 2024

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Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

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Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

21 March 2024

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21 March 2024

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Characterization of S6K2, a novel kinase homologous to S6K1

21 March 2024

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Branched chain amino acids activate messenger ribonucleic acid translation regulatory proteins in human skeletal muscle, and glucocorticoids blunt this action

21 March 2024

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Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies

21 March 2024

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21 March 2024

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Glucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1

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Phosphorylation and activation of p70s6k by PDK1

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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

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Identifiers

0 references

1 reference