(Q35560848)

English

Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport

scientific article published on May 2015

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport (English)

1 reference

Europe PubMed Central

8 August 2017

blood–brain barrier

1 reference

based on heuristic

inferred from title

Tetsuya Terasaki

object named as

Tetsuya Terasaki

5

0 references

Margareta Hammarlund-Udenaes

6

object named as

Margareta Hammarlund-Udenaes

1 reference

Europe PubMed Central

8 August 2017

author name string

Muhammad Waqas Sadiq

1

1 reference

Europe PubMed Central

8 August 2017

Yasuo Uchida

2

1 reference

Europe PubMed Central

8 August 2017

Yutaro Hoshi

3

1 reference

Europe PubMed Central

8 August 2017

Masanori Tachikawa

4

1 reference

Europe PubMed Central

8 August 2017

language of work or name

0 references

publication date

1 May 2015

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

10

1 reference

Europe PubMed Central

8 August 2017

5

1 reference

Europe PubMed Central

8 August 2017

e0118638

1 reference

Europe PubMed Central

8 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 May 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

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Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes

1 reference

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P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

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Identifiers

10.1371/JOURNAL.PONE.0118638

1 reference

Europe PubMed Central

8 August 2017

2015PLoSO..1018638S

0 references

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

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