(Q35561092)

8 August 2017

title

Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules (English)

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8 August 2017

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Adam J Costin

8

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Michael R. Hayden

object named as

Michael R Hayden

16

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author name string

Janine K Kruit

1

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8 August 2017

Nadeeja Wijesekara

2

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8 August 2017

Jocelyn E Manning Fox

3

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8 August 2017

Xiao-Qing Dai

4

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8 August 2017

Liam R Brunham

5

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8 August 2017

Gavin J Searle

6

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8 August 2017

Garry P Morgan

7

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8 August 2017

Renmei Tang

9

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8 August 2017

Alpana Bhattacharjee

10

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8 August 2017

James D Johnson

11

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8 August 2017

Peter E Light

12

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8 August 2017

Brad J Marsh

13

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8 August 2017

Patrick E Macdonald

14

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8 August 2017

C Bruce Verchere

15

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8 August 2017

language of work or name

English

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publication date

12 October 2011

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8 August 2017

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8 August 2017

volume

60

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8 August 2017

issue

12

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8 August 2017

page(s)

3186-3196

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

8 August 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3219942/fullTextXML

inferred from PubMed Central ID database lookup

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12 July 2018

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Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice

12 July 2018

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Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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SUMOylation regulates Kv2.1 and modulates pancreatic beta-cell excitability

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12 July 2018

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12 July 2018

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Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Insulin granule dynamics in pancreatic beta cells

12 July 2018

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells

12 July 2018

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Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

12 July 2018

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12 July 2018

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12 July 2018

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26 September 2018

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26 September 2018

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Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity

26 September 2018

1 reference

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Cholesterol facilitates the native mechanism of Ca2+-triggered membrane fusion

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Cholesterol Loading Induces a Block in the Exit of VSVG from the TGN

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Cholesterol-rich lipid rafts mediate akt-regulated survival in prostate cancer cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Risk for diabetes mellitus in middle-aged Caucasian male participants of the PROCAM study: implications for the definition of impaired fasting glucose by the American Diabetes Association. Prospective Cardiovascular Münster.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219942

Cholesterol Elevation Impairs Glucose-Stimulated Ca2+Signaling in Mouse Pancreatic β-Cells

26 September 2018

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12 December 2020

Diabetic dyslipidaemia

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12 December 2020

Direct Effect of Cholesterol on Insulin Secretion: A Novel Mechanism for Pancreatic -Cell Dysfunction

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12 December 2020

Cholesterol Depletion of Enterocytes

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12 December 2020

Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells

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12 December 2020

Identifiers

DOI

10.2337/DB11-0081

1 reference

8 August 2017

1 reference

8 August 2017

1 reference