(Q35561608)

8 August 2017

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title

Targeting oncogenic fusion genes in leukemias and lymphomas by RNA interference (English)

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8 August 2017

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1

Christine Damm-Welk

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author name string

Uta Fuchs

2

1 reference

8 August 2017

Wilhelm Wössmann

3

1 reference

8 August 2017

Arndt Borkhardt

4

1 reference

8 August 2017

language of work or name

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1 August 2003

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full work available at URL

8 August 2017

https://api.elsevier.com/content/article/PII:S1044579X03000427?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

https://api.elsevier.com/content/article/PII:S1044579X03000427?httpAccept=text/plain

22 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

Seminars in Cancer Biology

22 March 2024

published in

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8 August 2017

13

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8 August 2017

283-292

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8 August 2017

4

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Chromosomal translocations in human cancer.

8 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Translocations, master genes, and differences between the origins of acute and chronic leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Antisense therapeutics: is it as simple as complementary base recognition?

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Molecular mechanisms of action of antisense drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

1 reference

7 January 2021

Regulation of cell death by the Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Modeling Philadelphia chromosome positive leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

BCR/ABL: from molecular mechanisms of leukemia induction to treatment of chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

A comparison of the effect of bcr/abl breakpoint specific phosphothiorate oligodeoxynucleotides on colony formation by bcr/abl positive and negative, CD34 enriched mononuclear cell populations

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Effects of BCR-ABL antisense oligonucleotides (AS-ODN) on human chronic myeloid leukemic cells: AS-ODN as effective purging agents

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Masked antisense: a molecular configuration for discriminating similar RNA targets

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Kinetic selectivity of complementary nucleic acids: bcr-abl-directed antisense RNA and ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Ex vivo effects associated with the expression of a bcr-abl-specific ribozyme in a CML cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21).

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Designing of chimeric DNA/RNA hammerhead ribozymes to be targeted against AML1/MTG8 mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNAi: nature abhors a double-strand

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Ancient pathways programmed by small RNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

1 reference

7 January 2021

Post-transcriptional gene silencing by double-stranded RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Specific inhibition of bcr-abl gene expression by small interfering RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Translocations involving anaplastic lymphoma kinase (ALK).

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Expanding small RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNA interference: the new somatic cell genetics?

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Effective expression of small interfering RNA in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

The role of RNA editing by ADARs in RNAi

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Double-stranded RNA as a template for gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNAi is antagonized by A-->I hyper-editing

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Modelling haematopoietic malignancies in the mouse and therapeutical implications

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNA interference in adult mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Acute leukaemia in bcr/abl transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Humanbcr-abl gene has a lethal effect on embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900042-7

7 January 2021

Molecular genetics of human leukemia

4

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligodeoxynucleotides

22 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

Antisense BCR-ABL oligomers cause non-specific inhibition of chronic myeloid leukemia cell lines

22 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

Improved specificity of ribozyme-mediated cleavage of bcr-abl mRNA

22 March 2024

22

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity

22 March 2024

27

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA

22 March 2024

29

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

A ribozyme which discriminates in vitro between PML/RAR alpha, the t(15;17)-associated fusion RNA of acute promyelocytic leukemia, and PML and RAR alpha, the transcripts from the nonrearranged alleles

22 March 2024

31

1 reference

https://api.crossref.org/works/10.1016/S1044-579X(03)00042-7

22 March 2024

Identifiers

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8 August 2017

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