(Q35562915)

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Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut

scientific article published on 10 April 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

toll-like receptor

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acute lung injury

1 reference

based on heuristic

inferred from title

author name string

Chhinder P Sodhi

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Hongpeng Jia

2

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Yukihiro Yamaguchi

3

1 reference

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5 March 2020

Peng Lu

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Charlotte Egan

6

1 reference

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5 March 2020

John Ozolek

7

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Xiaorong Zhu

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

David J Hackam

10

1 reference

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5 March 2020

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10 April 2015

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5 March 2020

Journal of Immunology

1 reference

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5 March 2020

194

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5 March 2020

10

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5 March 2020

4931-4939

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

TLR-Dependent Human Mucosal Epithelial Cell Responses to Microbial Pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis, autophagy, and pyroptosis signaling.

1 reference

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12 July 2018

ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury

1 reference

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12 July 2018

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.

1 reference

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12 July 2018

Recognition of lipopolysaccharide pattern by TLR4 complexes

1 reference

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12 July 2018

In silico modeling: methods and applications to trauma and sepsis

1 reference

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12 July 2018

Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Pathogen recognition receptors: ligands and signaling pathways by Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Protein kinase C-ζ mediates lung injury induced by diesel exhaust particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Activation of toll-like receptor 4 is necessary for trauma hemorrhagic shock-induced gut injury and polymorphonuclear neutrophil priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Gut-origin sepsis: evolution of a concept

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Transcriptomic response of murine liver to severe injury and hemorrhagic shock: a dual-platform microarray analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Efferent vagal nerve stimulation attenuates acute lung injury following burn: The importance of the gut-lung axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC-ζ and PP2A pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Protein kinase C activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxygenation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: effects on tight junction structural proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Mediators of endoplasmic reticulum stress-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Incidence and outcomes of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

TLR4 antagonists for endotoxemia and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

12 July 2018

Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417407

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Tolerance, danger, and the extended family

1 reference

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12 July 2018

Intraluminal nonbacterial intestinal components control gut and lung injury after trauma hemorrhagic shock

1 reference

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26 September 2018

Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation

1 reference

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Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis.

1 reference

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Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock

1 reference

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26 September 2018

HMGB1 contributes to the development of acute lung injury after hemorrhage

1 reference

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26 September 2018

Acute lung injury after hemorrhagic shock is dependent on gut injury and sex.

1 reference

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26 September 2018

Systemic inflammation and remote organ injury following trauma require HMGB1

1 reference

https://pubmed.ncbi.nlm.nih.gov/25862813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-1 as a mediator of acute lung inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25862813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The global burden of injuries

1 reference

https://pubmed.ncbi.nlm.nih.gov/25862813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1402490

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25862813%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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