(Q35564420)

8 August 2017

title

Design, synthesis, and biological evaluation of ring-constrained novobiocin analogues as hsp90 C-terminal inhibitors (English)

1 reference

8 August 2017

3

Brian S J Blagg

1 reference

8 August 2017

Gaurav Garg

1

1 reference

8 August 2017

Huiping Zhao

series ordinal

2

1 reference

8 August 2017

publication date

12 December 2014

1 reference

ACS Medicinal Chemistry Letters

8 August 2017

published in

1 reference

8 August 2017

volume

6

1 reference

8 August 2017

issue

2

1 reference

8 August 2017

page(s)

204-209

1 reference

Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors

8 August 2017

cites work

1 reference

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3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition

27 July 2018

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Novobiocin analogues with second-generation noviose surrogates

27 July 2018

1 reference

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Hsp90 molecular chaperone inhibitors: are we there yet?

27 July 2018

1 reference

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Molecular design of anticancer drug leads based on three-dimensional quantitative structure-activity relationship

27 July 2018

1 reference

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Elucidation of the Hsp90 C-terminal inhibitor binding site

27 July 2018

1 reference

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HSP90 at the hub of protein homeostasis: emerging mechanistic insights

27 July 2018

1 reference

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To fold or not to fold: modulation and consequences of Hsp90 inhibition

27 July 2018

1 reference

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KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells

27 July 2018

1 reference

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Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket

27 July 2018

1 reference

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The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines

27 July 2018

1 reference

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Hsp90: a novel target for the disruption of multiple signaling cascades

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

A library of noviosylated coumarin analogues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Hsp90 as a target for drug development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

HSP90 and the chaperoning of cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Hsp90 inhibitors identified from a library of novobiocin analogues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

27 July 2018

The Hallmarks of Cancer

1 reference

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High-throughput screen of natural product libraries for hsp90 inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Synthesis and Evaluation of Noviose Replacements on Novobiocin that Manifest Anti-proliferative Activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329597

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25699150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis and evaluation of coumermycin A1 analogues that inhibit the Hsp90 protein folding machinery

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25699150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML5004475

1 reference

8 August 2017

1 reference

8 August 2017

1 reference