(Q35564607)

8 August 2017

title

Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18. (English)

1 reference

8 August 2017

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Plasmodium falciparum

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Shailesh N Mistry

5

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Nyssa Drinkwater

object named as

Nyssa Drinkwater

4

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Sheena McGowan

object named as

Sheena McGowan

7

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Peter J. Scammells

object named as

Peter J Scammells

6

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author name string

Alessandro Paiardini

1

1 reference

8 August 2017

Rebecca S Bamert

2

1 reference

8 August 2017

Komagal Kannan-Sivaraman

3

1 reference

8 August 2017

language of work or name

1 reference

20 February 2015

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8 August 2017

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8 August 2017

volume

10

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8 August 2017

issue

2

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8 August 2017

page(s)

e0115859

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Creative Commons Attribution 4.0 International

8 August 2017

copyright license

start time

20 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

Working in concert: the metalloaminopeptidases from Plasmodium falciparum

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

The open access malaria box: a drug discovery catalyst for neglected diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria

27 July 2018

1 reference

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MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

27 July 2018

1 reference

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Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases

27 July 2018

1 reference

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Distribution and biochemical properties of an M1-family aminopeptidase in Plasmodium falciparum indicate a role in vacuolar hemoglobin catabolism

27 July 2018

1 reference

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Synthesis of New (−)-Bestatin-Based Inhibitor Libraries Reveals a Novel Binding Mode in the S1 Pocket of the Essential Malaria M1 Metalloaminopeptidase

27 July 2018

1 reference

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Metallo-aminopeptidase inhibitors

27 July 2018

1 reference

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Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases

27 July 2018

1 reference

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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

27 July 2018

1 reference

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Protein structure modeling with MODELLER

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development

27 July 2018

1 reference

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MolDock: a new technique for high-accuracy molecular docking

27 July 2018

1 reference

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

27 July 2018

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

Zinc-binding groups modulate selective inhibition of MMPs

27 July 2018

1 reference

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The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4336144

10.1371/JOURNAL.PONE.0115859

26 September 2018

Identifiers

DOI

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8 August 2017

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1 reference

8 August 2017

1 reference