(Q35568516)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Manoj Bhasin

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

13

Sabina Signoretti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Liang Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Xiaoen Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Andrea J Bullock

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Marcella Callea

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Harleen Shah

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Jiaxi Song

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Kelli Moreno

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Barbara Visentin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Douglas Deutschman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Michael B Atkins

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

James W Mier

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Roger A Sabbadini

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Rupal S Bhatt

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

English

0 references

publication date

14 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

1925-1934

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

27 February 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4419371

inferred from PubMed Central ID database lookup

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12 July 2018

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Overall survival for sorafenib plus interleukin-2 compared with sorafenib alone in metastatic renal cell carcinoma (mRCC): final results of the ROSORC trial

12 July 2018

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Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways

12 July 2018

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Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts.

12 July 2018

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Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers

12 July 2018

1 reference

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Hypoxia, therapeutic resistance, and sphingosine 1-phosphate

12 July 2018

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First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer.

12 July 2018

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Sphingosine kinase-1 inhibition sensitizes curcumin-induced growth inhibition and apoptosis in ovarian cancer cells

12 July 2018

1 reference

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Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.

12 July 2018

1 reference

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Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression

12 July 2018

1 reference

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Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3K/Akt/NF-κB pathway in human non-small cell lung cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine‐1‐phosphate antibodies as potential agents in the treatment of cancer and age‐related macular degeneration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Renal cancer resistance to antiangiogenic therapy is delayed by restoration of angiostatic signaling.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine 1-phosphate and cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Targeting sphingosine 1-phosphate (S1P) levels and S1P receptor functions for therapeutic immune interventions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting

12 July 2018

1 reference

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Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial

12 July 2018

1 reference

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

12 July 2018

1 reference

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Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival

12 July 2018

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Resistance to targeted therapy in renal-cell carcinoma

12 July 2018

1 reference

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Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies

12 July 2018

1 reference

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Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma

12 July 2018

1 reference

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12 July 2018

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1 reference

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Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.

12 July 2018

1 reference

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Resistance to chemotherapy: new treatments and novel insights into an old problem

12 July 2018

1 reference

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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

12 July 2018

1 reference

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Modes of resistance to anti-angiogenic therapy

12 July 2018

1 reference

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Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

12 July 2018

1 reference

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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

12 July 2018

1 reference

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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

12 July 2018

1 reference

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Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

12 July 2018

1 reference

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Novel approaches in the therapy of metastatic renal cell carcinoma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Cell type-specific localization of sphingosine kinase 1a in human tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

An oncogenic role of sphingosine kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Predictive value of sphingosine kinase 1 expression in neoadjuvant treatment of breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419371

Overall survival in renal-cell carcinoma with pazopanib versus sunitinib

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25589614

12 December 2020

inferred from PubMed ID database lookup

Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25589614

12 December 2020

inferred from PubMed ID database lookup

Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25589614

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1078-0432.CCR-14-2031

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589614%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

25589614

1 reference