(Q35569060)

8 August 2017

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title

Antimalarial chemotherapy: young guns or back to the future? (English)

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8 August 2017

0 references

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3

Alexis Nzila

1 reference

8 August 2017

1

Giancarlo A. Biagini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580958

25 March 2024

4

Stephen A. Ward

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580958

25 March 2024

author name string

Giancarlo A Biagini

1

1 reference

8 August 2017

Paul M O'Neill

2

1 reference

8 August 2017

Stephen A Ward

4

1 reference

8 August 2017

Patrick G Bray

5

1 reference

8 August 2017

Paul M. O'Neill

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580958

25 March 2024

Patrick G. Bray

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580958

25 March 2024

language of work or name

1 reference

1 November 2003

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full work available at URL

8 August 2017

https://api.elsevier.com/content/article/PII:S1471492203002514?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

https://api.elsevier.com/content/article/PII:S1471492203002514?httpAccept=text/plain

25 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

25 March 2024

published in

Trends in Parasitology

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8 August 2017

volume

19

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8 August 2017

issue

11

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8 August 2017

page(s)

479-487

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Chloroquine-resistant malaria

8 August 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

4-Aminoquinolines--past, present, and future: a chemical perspective

25 March 2024

2

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

The effect of fluorine substitution on the metabolism and antimalarial activity of amodiaquine.

25 March 2024

3

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Effect of disposition of mannich antimalarial agents on their pharmacology and toxicology.

25 March 2024

4

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

New 4-aminoquinoline Mannich base antimalarials. 1. Effect of an alkyl substituent in the 5'-position of the 4'-hydroxyanilino side chain.

25 March 2024

5

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum

25 March 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Novel short chain chloroquine analogues retain activity against chloroquine resistant K1 Plasmodium falciparum

25 March 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents

25 March 2024

9

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds

25 March 2024

10

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Ring opening of artemisinin (qinghaosu) and dihydroartemisinin and interception of the open hydroperoxides with Formation of N-oxides — a chemical model for antimalarial mode of action

25 March 2024

12

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues

25 March 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Artemisinin and derivatives: the future for malaria treatment?

25 March 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents

25 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides

25 March 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs

25 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

25 March 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum

25 March 2024

19

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

25 March 2024

20

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania

25 March 2024

21

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses

25 March 2024

22

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs

25 March 2024

24

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.

25 March 2024

25

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

25 March 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug

25 March 2024

27

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Iron, but not folic acid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria

25 March 2024

28

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance

25 March 2024

29

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Chemosensitization of Plasmodium falciparum by probenecid in vitro

25 March 2024

30

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Plasmodium falciparum: In vitro induction of resistance to aminopterin

25 March 2024

31

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

25 March 2024

32

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Sulfa drugs strike more than once

25 March 2024

33

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Transport of phospholipid synthesis precursors and lipid trafficking into malaria-infected erythrocytes

25 March 2024

36

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

A class of potent antimalarials and their specific accumulation in infected erythrocytes

25 March 2024

38

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Diamidine compounds: selective uptake and targeting in Plasmodium falciparum.

25 March 2024

39

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Heme binding contributes to antimalarial activity of bis-quaternary ammoniums

25 March 2024

40

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

A plastid organelle as a drug target in apicomplexan parasites.

25 March 2024

41

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

25 March 2024

43

1 reference

https://api.crossref.org/works/10.1016/J.PT.2003.09.011

Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

25 March 2024

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Identifiers

1 reference

8 August 2017

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