(Q35571875)

8 August 2017

1 reference

title

Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice (English)

1 reference

8 August 2017

0 references

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1218-1

26 March 2024

author name string

Y. Yang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14586501

26 March 2024

P. Santamaria

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14586501

26 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14586501

26 March 2024

publication date

28 October 2003

1 reference

full work available at URL

8 August 2017

https://link.springer.com/content/pdf/10.1007/s00125-003-1218-1.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14586501

http://link.springer.com/content/pdf/10.1007/s00125-003-1218-1.pdf

26 March 2024

file format

Portable Document Format

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/S00125-003-1218-1

http://link.springer.com/article/10.1007/s00125-003-1218-1/fulltext.html

26 March 2024

1 reference

https://api.crossref.org/works/10.1007/S00125-003-1218-1

http://link.springer.com/content/pdf/10.1007/s00125-003-1218-1

26 March 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/S00125-003-1218-1

26 March 2024

1 reference

8 August 2017

46

1 reference

8 August 2017

11

1 reference

8 August 2017

1447-1464

1 reference

https://scigraph.springernature.com/pub.10.1007/s00125-003-1218-1

8 August 2017

0 references

cites work

Cytokines and chemokines in the pathogenesis of murine type 1 diabetes.

1 reference

12 December 2020

In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

1 reference

12 December 2020

Dominant role of intercellular adhesion molecule-1 in the pathogenesis of autoimmune diabetes in non-obese diabetic mice

1 reference

12 December 2020

Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

1 reference

12 December 2020

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

1 reference

12 December 2020

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

1 reference

12 December 2020

Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.

1 reference

12 December 2020

Impact of genetic and non-genetic factors in type 1 diabetes

1 reference

12 December 2020

Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1

1 reference

12 December 2020

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

1 reference

12 December 2020

Mechanism underlying counterregulation of autoimmune diabetes by IL-4.

1 reference

12 December 2020

Subcongenic analysis of the Idd13 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for beta 2-microglobulin.

1 reference

12 December 2020

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

1 reference

12 December 2020

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

12 December 2020

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

1 reference

12 December 2020

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.

1 reference

12 December 2020

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

1 reference

12 December 2020

Insulin-dependent diabetes mellitus

1 reference

12 December 2020

CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes

1 reference

12 December 2020

Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells

1 reference

12 December 2020

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

1 reference

12 December 2020

Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping

1 reference

12 December 2020

Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II.

1 reference

12 December 2020

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

1 reference

12 December 2020

Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

1 reference

12 December 2020

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

1 reference

12 December 2020

Mapping by Genetic Interaction: High-Resolution Congenic Mapping of the Type 1 Diabetes Loci Idd10 and Idd18 in the NOD Mouse

1 reference

12 December 2020

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

1 reference

12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Induction of tolerance in murine autoimmune diabetes by transient blockade of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway

1 reference

12 December 2020

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

1 reference

12 December 2020

Either IL-2 or IL-12 is sufficient to direct Th1 differentiation by nonobese diabetic T cells.

1 reference

12 December 2020

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

1 reference

12 December 2020

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

1 reference

12 December 2020

Three Loci on Mouse Chromosome 6 Influence Onset and Final Incidence of Type I Diabetes in NOD.C3H Congenic Strains

1 reference

12 December 2020

Deviation of pancreas-infiltrating cells to Th2 by interleukin-12 antagonist administration inhibits autoimmune diabetes

1 reference

12 December 2020

Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules

1 reference

12 December 2020

The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model

1 reference

12 December 2020

IL-10 impacts autoimmune diabetes via a CD8+ T cell pathway circumventing the requirement for CD4+ T and B lymphocytes

1 reference

12 December 2020

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

12 December 2020

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci

1 reference

12 December 2020

Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice

1 reference

12 December 2020

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

1 reference

12 December 2020

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice

1 reference

12 December 2020

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

12 December 2020

The effect of bone marrow and thymus chimerism between non-obese diabetic (NOD) and NOD-E transgenic mice, on the expression and prevention of diabetes

1 reference

12 December 2020

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

1 reference

12 December 2020

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

1 reference

12 December 2020

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

1 reference

12 December 2020

Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets

1 reference

12 December 2020

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

1 reference

12 December 2020

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice

1 reference

12 December 2020

Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide

1 reference

12 December 2020

RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes

1 reference

12 December 2020

An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

1 reference

12 December 2020

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

12 December 2020

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

1 reference

12 December 2020

Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo

1 reference

12 December 2020

Interleukin-4 deficiency does not exacerbate disease in NOD mice.

1 reference

12 December 2020

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

12 December 2020

Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice

1 reference

12 December 2020

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

1 reference

12 December 2020

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

1 reference

12 December 2020

Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells

1 reference

12 December 2020

Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells

1 reference

12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

12 December 2020

CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer

1 reference

12 December 2020

B lymphocytes not required for progression from insulitis to diabetes in non-obese diabetic mice

1 reference

12 December 2020

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

Induction of type I diabetes by interferon-alpha in transgenic mice

1 reference

12 December 2020

Interleukin-13 prevents autoimmune diabetes in NOD mice

1 reference

12 December 2020

A key role for ICAM-1 in generating effector cells mediating inflammatory responses

1 reference

12 December 2020

L-selectin is not required for T cell-mediated autoimmune diabetes

1 reference

12 December 2020

The role of cytokines as effectors of tissue destruction in autoimmunity

1 reference

12 December 2020

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

1 reference

12 December 2020

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

1 reference

12 December 2020

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

1 reference

12 December 2020

The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7

1 reference

12 December 2020

MHC-linked protection from diabetes dissociated from clonal deletion of T cells

1 reference

12 December 2020

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes

1 reference

12 December 2020

Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

1 reference

12 December 2020

Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice

1 reference

12 December 2020

Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice

1 reference

12 December 2020

Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease

1 reference

12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

12 December 2020

Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice

1 reference

12 December 2020

Significant role for Fas in the pathogenesis of autoimmune diabetes.

1 reference

12 December 2020

CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells

1 reference

12 December 2020

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

1 reference

12 December 2020

Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice

1 reference

12 December 2020

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

1 reference

12 December 2020

Cutting edge: homologous recombination of the MHC class I K region defines new MHC-linked diabetogenic susceptibility gene(s) in nonobese diabetic mice

1 reference

12 December 2020

Acceleration of the onset of diabetes in NOD mice by thymectomy at weaning

1 reference

12 December 2020

Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice.

1 reference

12 December 2020

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

1 reference

12 December 2020

T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes

1 reference

12 December 2020

Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse Chromosome 3

1 reference

12 December 2020

Prevention of a Th1 disease by a Th1 cytokine: IL-12 and diabetes in NOD mice

1 reference

12 December 2020

Reevaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain.

1 reference

12 December 2020

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

1 reference

12 December 2020

Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice

1 reference

12 December 2020

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

12 December 2020

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

1 reference

12 December 2020

Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes

1 reference

12 December 2020

Development of insulitis and diabetes in B cell-deficient NOD mice

1 reference

12 December 2020

Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway.

1 reference

12 December 2020

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

1 reference

12 December 2020

In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes

1 reference

12 December 2020

Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background

1 reference

12 December 2020

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

1 reference

12 December 2020

Prevention of autoimmune insulitis in nonobese diabetic mice by expression of major histocompatibility complex class I Ld molecules

1 reference

12 December 2020

Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjögren's syndrome-like autoimmune exocrinopathy

1 reference

12 December 2020

Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1

1 reference

12 December 2020

Intrinsic defects in the T-cell lineage results in natural killer T-cell deficiency and the development of diabetes in the nonobese diabetic mouse.

1 reference

12 December 2020

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice

1 reference

12 December 2020

A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice

1 reference

12 December 2020

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

1 reference

12 December 2020

Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci.

1 reference

12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

12 December 2020

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

1 reference

12 December 2020

TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype

1 reference

12 December 2020

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

1 reference

12 December 2020

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus

1 reference

12 December 2020

Crosses of NOD mice with the related NON strain. A polygenic model for IDDM

1 reference

12 December 2020

NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

1 reference

12 December 2020

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

1 reference

12 December 2020

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

1 reference

12 December 2020

Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment.

1 reference

12 December 2020

The effects of a nonimmunogenic form of murine soluble interferon-gamma receptor on the development of autoimmune diabetes in the NOD mouse

1 reference

12 December 2020

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

1 reference

12 December 2020

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

12 December 2020

Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

1 reference

12 December 2020

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

12 December 2020

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

12 December 2020

Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene.

1 reference

12 December 2020

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

1 reference

12 December 2020

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

1 reference

12 December 2020

Human DQ8 can substitute for murine I-Ag7 in the selection of diabetogenic T cells restricted to I-Ag7

1 reference

12 December 2020

An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells

1 reference

12 December 2020

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

1 reference

12 December 2020

Pathogenesis of virus-induced diabetes in mice

1 reference

12 December 2020

Multistage regulation of Th1-type immune responses by the transcription factor IRF-1

1 reference

12 December 2020

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

1 reference

12 December 2020

The role of viruses in type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals

1 reference

12 December 2020

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

1 reference

12 December 2020

Interleukin 12 mRNA expression in islets correlates with beta-cell destruction in NOD mice

1 reference

12 December 2020

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

12 December 2020

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

1 reference

12 December 2020

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

1 reference

12 December 2020

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

12 December 2020

Genetic Analysis of Autoimmune Sialadenitis in Nonobese Diabetic Mice: A Major Susceptibility Region on Chromosome 1

1 reference

12 December 2020

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities

1 reference

12 December 2020

Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation.

1 reference

12 December 2020

Mechanisms of beta cell death in diabetes: a minor role for CD95.

1 reference

12 December 2020

ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.

1 reference

12 December 2020

B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

1 reference

12 December 2020

Accelerated diabetes in rat insulin promoter-tumor necrosis factor-alpha transgenic nonobese diabetic mice lacking major histocompatibility class II molecules

1 reference

12 December 2020

Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.

1 reference

12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

1 reference

12 December 2020

Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals

1 reference

12 December 2020

Immunoregulation by cytokines in autoimmune diabetes

1 reference

12 December 2020

Autoantigen-independent deletion of diabetogenic CD4+ thymocytes by protective MHC class II molecules

1 reference

12 December 2020

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

12 December 2020

Consequences of in situ production of IL-2 for islet cell death.

1 reference

12 December 2020

The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice

1 reference

12 December 2020

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

12 December 2020

Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice

1 reference

12 December 2020

The role of viruses in human diabetes.

1 reference

12 December 2020

Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.

1 reference

12 December 2020

T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice

1 reference

12 December 2020

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

1 reference

12 December 2020

Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

1 reference

12 December 2020

Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene.

1 reference

12 December 2020

Coxsackievirus immunization delays onset of diabetes in non-obese diabetic mice

1 reference

12 December 2020

CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis

1 reference

12 December 2020

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice

1 reference

12 December 2020

Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice

1 reference

12 December 2020

An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice

1 reference

12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

1 reference

12 December 2020

A mechanism for IL-10-mediated diabetes in the nonobese diabetic (NOD) mouse: ICAM-1 deficiency blocks accelerated diabetes

1 reference

12 December 2020

Genetic control of autoimmune diabetes in the NOD mouse

1 reference

12 December 2020

Interleukin 12 and autoimmune diabetes

1 reference

12 December 2020

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

1 reference

12 December 2020

TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes

1 reference

12 December 2020

The role of Fas in autoimmune diabetes

1 reference

12 December 2020

Genetic requirements for acceleration of diabetes in non-obese diabetic mice expressing interleukin-2 in islet beta-cells

1 reference

12 December 2020

The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137.

1 reference

12 December 2020

Thymic positive selection and peripheral activation of islet antigen-specific T cells: separation of two diabetogenic steps by an I-A(g7) class II MHC beta-chain mutant

1 reference

12 December 2020

Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

1 reference

12 December 2020

Identifiers

DOI

1 reference

8 August 2017

1 reference