(Q35575289)

8 August 2017

1 reference

title

Rab proteins and endocytic trafficking: potential targets for therapeutic intervention (English)

1 reference

8 August 2017

pharmaceutical science

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

28 March 2024

author

Angela Wandinger-Ness

3

object named as

Angela Wandinger-Ness

1 reference

8 August 2017

Mary-Pat Stein

1

1 reference

8 August 2017

Jianbo Dong

2

1 reference

8 August 2017

language of work or name

English

0 references

publication date

1 November 2003

1 reference

8 August 2017

14 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14597139

full work available at URL

28 March 2024

https://api.elsevier.com/content/article/PII:S0169409X03001613?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

https://api.elsevier.com/content/article/PII:S0169409X03001613?httpAccept=text/plain

28 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Advanced Drug Delivery Reviews

28 March 2024

published in

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8 August 2017

55

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8 August 2017

11

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8 August 2017

1421-1437

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Regulated portals of entry into the cell

8 August 2017

1

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Direct interactions between rab GTPases and cargo

28 March 2024

2

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab proteins as membrane organizers

28 March 2024

5

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab15 mediates an early endocytic event in Chinese hamster ovary cells

28 March 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway

28 March 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab proteins in gastric parietal cells: evidence for the membrane recycling hypothesis

28 March 2024

9

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab 7: an important regulator of late endocytic membrane traffic

28 March 2024

10

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

28 March 2024

11

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab9 functions in transport between late endosomes and the trans Golgi network

28 March 2024

12

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

28 March 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The endocytic catalysts, Rab5a and Rab7, are tandem regulators of thyroid hormone production

28 March 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

28 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Regulation of G-protein-coupled receptor activity by rab GTPases

28 March 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells

28 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Late endosome motility depends on lipids via the small GTPase Rab7.

28 March 2024

18

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Role of Rab GTPases in membrane traffic

28 March 2024

19

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Interferon-gamma selectively induces Rab5a synthesis and processing in mononuclear cells

28 March 2024

20

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Differentially expressed CC3/TIP30 and rab11 along in vivo and in vitro intestinal epithelial cell crypt-villus axis

28 March 2024

21

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The molecular pathology of Barrett's esophagus

28 March 2024

22

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy

28 March 2024

23

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Differentially expressed genes associated with mouse lung tumor progression

28 March 2024

24

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors

28 March 2024

25

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues.

28 March 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Geranylgeranyl switching regulates GDI-Rab GTPase recycling

28 March 2024

28

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex

28 March 2024

29

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Prenylation of Rab GTPases: molecular mechanisms and involvement in genetic disease.

28 March 2024

30

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI

28 March 2024

31

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Specific interactions of Mss4 with members of the Rab GTPase subfamily.

28 March 2024

32

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones

28 March 2024

33

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mammalian suppressor of Sec4 modulates the inhibitory effect of Rab15 during early endocytosis

28 March 2024

34

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome

28 March 2024

35

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins

28 March 2024

36

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

28 March 2024

37

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex

28 March 2024

38

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex

28 March 2024

39

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Role of Rab5 in the Recruitment of hVps34/p150 to the Early Endosome

28 March 2024

40

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab5 regulates motility of early endosomes on microtubules

28 March 2024

41

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

28 March 2024

42

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase.

28 March 2024

43

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Phosphoinositide recognition domains

28 March 2024

44

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1

28 March 2024

45

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The phosphatidylinositol 3-phosphate-binding FYVE finger

28 March 2024

46

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

28 March 2024

48

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells

28 March 2024

49

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking

28 March 2024

50

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of residues in TIP47 essential for Rab9 binding

28 March 2024

51

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

28 March 2024

52

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

28 March 2024

53

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A syndrome associating partial albinism and immunodeficiency

28 March 2024

54

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

28 March 2024

55

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

28 March 2024

57

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

28 March 2024

58

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Hypomelanosis, immunity, central nervous system: no more "and", not the end

28 March 2024

59

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Griscelli syndrome types 1 and 2.

28 March 2024

60

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene

28 March 2024

61

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

28 March 2024

62

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes

28 March 2024

63

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes

28 March 2024

64

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy

28 March 2024

65

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

28 March 2024

66

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases

28 March 2024

67

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta

28 March 2024

68

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease

28 March 2024

69

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Non-specific X-linked semidominant mental retardation by mutations in a Rab GDP-dissociation inhibitor.

28 March 2024

70

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

28 March 2024

71

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mutations in GDI1 are responsible for X-linked non-specific mental retardation

28 March 2024

73

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

28 March 2024

74

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles

28 March 2024

75

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

28 March 2024

76

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene

28 March 2024

77

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Extra Rabs unsnarl a lipid traffic jam

28 March 2024

78

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Protein kinase B/akt and rab5 mediate Ras activation of endocytosis

28 March 2024

79

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex

28 March 2024

80

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading

28 March 2024

81

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins

28 March 2024

82

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

28 March 2024

83

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The small GTP-binding protein rab4 is associated with early endosomes

28 March 2024

84

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling

28 March 2024

85

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

rab5 controls early endosome fusion in vitro

28 March 2024

86

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

28 March 2024

87

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

28 March 2024

88

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

28 March 2024

89

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab7: a key to lysosome biogenesis

28 March 2024

90

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes

28 March 2024

91

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab11 regulates recycling through the pericentriolar recycling endosome

28 March 2024

92

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25

28 March 2024

93

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor

28 March 2024

94

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion

28 March 2024

96

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The phagosome proteome: insight into phagosome functions

28 March 2024

97

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells

28 March 2024

98

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells

28 March 2024

99

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation

28 March 2024

103

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein

28 March 2024

104

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis

28 March 2024

105

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic

28 March 2024

106

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5

28 March 2024

107

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesicles

28 March 2024

108

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.

28 March 2024

109

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

The Rab5 effector EEA1 is a core component of endosome docking

28 March 2024

110

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

28 March 2024

111

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion

28 March 2024

112

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

28 March 2024

113

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

28 March 2024

114

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5

28 March 2024

115

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A novel Rab9 effector required for endosome-to-TGN transport

28 March 2024

116

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Role of Rab9 GTPase in facilitating receptor recruitment by TIP47

28 March 2024

117

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes

28 March 2024

118

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins

28 March 2024

119

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Identification of a putative effector protein for rab11 that participates in transferrin recycling

28 March 2024

120

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling

28 March 2024

121

1 reference

https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells

28 March 2024

122

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https://api.crossref.org/works/10.1016/J.ADDR.2003.07.009

28 March 2024

Identifiers

1 reference

8 August 2017

1 reference