(Q35578043)

9 August 2017

1 reference

title

Aging or osteoarthritis: which is the problem? (English)

1 reference

9 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14603576

Musculoskeletal Development

29 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14603576

29 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

29 March 2024

1

Richard F Loeser

1 reference

9 August 2017

Najia Shakoor

2

1 reference

9 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14603576

29 March 2024

publication date

1 November 2003

1 reference

full work available at URL

9 August 2017

https://api.elsevier.com/content/article/PII:S0889857X03000620?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

https://api.elsevier.com/content/article/PII:S0889857X03000620?httpAccept=text/plain

29 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Rheumatic Diseases Clinics of North America

29 March 2024

published in

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9 August 2017

volume

29

1 reference

9 August 2017

issue

4

1 reference

9 August 2017

page(s)

653-673

1 reference

Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS)

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian women

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthritis in cynomolgus macaques. III: Effects of age, gender, and subchondral bone thickness on the severity of disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Genetics and osteoarthritis: exposing the iceberg

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteo-Arthrosis: Prevalence in the Population and Relationship between Symptoms andX-ray Changes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Distinguishing ankle and knee articular cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Molecular basis for differences between human joints

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Healthy centenarians do not exist, but autonomous centenarians do: a population-based study of morbidity among Danish centenarians

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Some biochemical and biophysical parameters for the study of the pathogenesis of osteoarthritis: a comparison between the processes of ageing and degeneration in human hip cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Growth factor responsiveness of human articular chondrocytes in aging and development

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Telomere erosion and senescence in human articular cartilage chondrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Articular chondrocytes from aging rats respond poorly to insulin-like growth factor-1: an altered signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Oxidants, oxidative stress and the biology of ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Detection of superoxide and NADPH oxidase in porcine articular chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Nitric oxide in osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effect of collagen turnover on the accumulation of advanced glycation end products

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Matrix homeostasis in aging normal human ankle cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthritis and articular chondrocalcinosis in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Transglutaminase activity in aging articular chondrocytes and articular cartilage vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Strength and Muscle Quality in a Well-Functioning Cohort of Older Adults: The Health, Aging and Body Composition Study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Subchondral bone of the human knee joint in aging and osteoarthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Abnormal cancellous bone collagen metabolism in osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Increased knee joint loads during walking are present in subjects with knee osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Knee adduction moment, serum hyaluronan level, and disease severity in medial tibiofemoral osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Dynamic load at baseline can predict radiographic disease progression in medial compartment knee osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Quadriceps Weakness and Osteoarthritis of the Knee

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Quadriceps function, proprioceptive acuity and functional performance in healthy young, middle-aged and elderly subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

The size and strength of the quadriceps muscles of old and young men.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Laxity in healthy and osteoarthritic knees

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

The association between varus-valgus alignment and patellofemoral osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

The Role of Knee Alignment in Disease Progression and Functional Decline in Knee Osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Vertical impact increase in middle age may explain idiopathic weight-bearing joint osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Relationship between quadriceps strength and rate of loading during gait in women

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effect of fatigue on joint position sense of the knee

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Exercise-related knee joint laxity

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Pain thresholds and electromyographic features of periarticular muscles in patients with osteoarthritis of the knee

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Knee pain and joint loading in subjects with osteoarthritis of the knee

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effect of knee pain on joint loading in patients with osteoarthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Physical activity levels among the general US adult population and in adults with and without arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effect of age and activity on knee joint proprioception

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Joint injury in young adults and risk for subsequent knee and hip osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: the influence of time and age.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Association of estrogen replacement therapy with the risk of osteoarthritis of the hip in elderly white women. Study of Osteoporotic Fractures Research Group

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Estrogen Replacement Therapy and the Development of Osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Estrogen replacement therapy and worsening of radiographic knee osteoarthritis: the Framingham Study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Effects of long-term estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Obesity and Knee Osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthritis: new insights. Part 1: the disease and its risk factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Obesity and osteoarthritis of the knee: hypotheses concerning the relationship between ground reaction forces and quadriceps fatigue in long-duration walking

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Genetic influences on osteoarthritis in women: a twin study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: the Framingham Study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Prevalence of generalised osteoarthritis in patients with advanced hip and knee osteoarthritis: the Ulm Osteoarthritis Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Association of mild acetabular dysplasia with an increased risk of incident hip osteoarthritis in elderly white women: the study of osteoporotic fractures

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

The aetiology of primary osteoarthritis of the hip

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthritis in the elderly: clinical and radiological findings in 79 and 85 year olds

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Association of radiographic features of osteoarthritis of the knee with knee pain: Data from the baltimore longitudinal study of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Sensorimotor changes and functional performance in patients with knee osteoarthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Quadriceps weakness in knee osteoarthritis: the effect on pain and disability

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Baseline balance and functional decline in older adults with knee pain: the Observational Arthritis Study in Seniors

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Improvements in quadriceps sensorimotor function and disability of patients with knee osteoarthritis following a clinically practicable exercise regime.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900062-0

7 January 2021

Osteoarthrosis in guinea pigs: histopathologic and scanning electron microscopic features

4

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Differential effects of aging on human chondrocyte responses to transforming growth factor-β: Increased pyrophosphate production and decreased cell proliferation

29 March 2024

39

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

29 March 2024

Muscle changes in aging

40

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Osteoarthritis of the knee: effects on gait, strength, and flexibility

29 March 2024

54

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Adduction moment of the knee compared to radiological and clinical parameters in moderate medical osteoarthrosis of the knee

29 March 2024

73

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

A comparison of lower extremity muscle strength, obesity, and depression scores in elderly subjects with knee pain with and without radiographic evidence of knee osteoarthritis

29 March 2024

95

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Knee osteoarthritis compromises early mobility function: The Women's Health and Aging Study II

29 March 2024

105

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

Physical therapy is effective for patients with osteoarthritis of the knee: a randomized controlled clinical trial

29 March 2024

112

1 reference

https://api.crossref.org/works/10.1016/S0889-857X(03)00062-0

29 March 2024

Identifiers

1 reference

9 August 2017

1 reference