(Q35578938)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer (English)

1 reference

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2 March 2020

0 references

1 reference

3

1 reference

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2 March 2020

Xianjun Yu

20

1 reference

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2 March 2020

12

Liang Liu

1 reference

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2 March 2020

11

Dingkong Liang

1 reference

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2 March 2020

author name string

Shunrong Ji

1

1 reference

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2 March 2020

Yi Qin

2

1 reference

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2 March 2020

Xiangyuan Liu

4

1 reference

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2 March 2020

Hongli Hu

5

1 reference

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2 March 2020

Hu Zhou

6

1 reference

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2 March 2020

Jing Gao

7

1 reference

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2 March 2020

Bo Zhang

8

1 reference

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2 March 2020

Wenyan Xu

9

1 reference

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2 March 2020

Jiang Liu

10

1 reference

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2 March 2020

Chen Liu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jiang Long

14

1 reference

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2 March 2020

Haijun Zhou

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Paul J Chiao

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jin Xu

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Quanxing Ni

18

1 reference

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2 March 2020

Daming Gao

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

10 March 2015

1 reference

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2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

25

1 reference

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2 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

561-573

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

2 March 2020

copyright license

start time

10 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/cr.2015.30

0 references

cites work

Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Aberrant regulation of FBW7 in cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Oncogenic KRAS signalling in pancreatic cancer

12 July 2018

1 reference

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Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Recent progress in pancreatic cancer

12 July 2018

1 reference

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Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.

12 July 2018

1 reference

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

12 July 2018

1 reference

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Targeting the Ras-ERK pathway in pancreatic adenocarcinoma.

12 July 2018

1 reference

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Genetic basis of pancreas cancer development and progression: insights from whole-exome and whole-genome sequencing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Screening for pancreatic cancer: why, how, and who?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Expression of c-Myc and Fas correlates with perineural invasion of pancreatic cancer.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

What we have learned about pancreatic cancer from mouse models.

12 July 2018

1 reference

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Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma

12 July 2018

1 reference

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Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project

12 July 2018

1 reference

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MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma

12 July 2018

1 reference

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

12 July 2018

1 reference

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Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc

12 July 2018

1 reference

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Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas

12 July 2018

1 reference

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Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Hyperactive Ras in developmental disorders and cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Phosphorylation and ubiquitination of the transcription factor sterol regulatory element-binding protein-1 in response to DNA binding.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

DNA copy number losses in human neoplasms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Transformation of mammalian cells by constitutively active MAP kinase kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Determination of subcutaneous tumor size in athymic (nude) mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Immunohistochemically detected expression of 3 major genes (CDKN2A/p16, TP53, and SMAD4/DPC4) strongly predicts survival in patients with resectable pancreatic cancer.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423074

1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience

26 September 2018

1 reference

12 December 2020

Acinar-to-ductal metaplasia accompanies c-myc-induced exocrine pancreatic cancer progression in transgenic rodents

1 reference

12 December 2020

Loss of FBXW7 expression is associated with poor prognosis in intrahepatic cholangiocarcinoma

1 reference

12 December 2020

Myc and cell cycle control.

1 reference

12 December 2020

Impact of MYC in regulation of tumor cell metabolism

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCR.2015.30

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CR.2015.30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25753158%20AND%20SRC:MED&resulttype=core&format=json