(Q34788849)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21368833%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21368833%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

1 reference

4

1 reference

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24 January 2020

Alejandro Gutierrez

9

1 reference

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24 January 2020

Andrew L. Kung

16

1 reference

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24 January 2020

15

Steven P Gygi

1 reference

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24 January 2020

19

Ronald A DePinho

1 reference

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24 January 2020

17

Thomas Look

1 reference

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24 January 2020

1

Hiroyuki Inuzuka

1 reference

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24 January 2020

20

Wenyi Wei

1 reference

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24 January 2020

8

Lixin Wan

1 reference

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24 January 2020

2

Shavali Shaik

1 reference

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24 January 2020

author name string

Ichiro Onoyama

3

1 reference

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24 January 2020

Alan Tseng

5

1 reference

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24 January 2020

Richard S Maser

6

1 reference

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24 January 2020

Bo Zhai

7

1 reference

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24 January 2020

Alan W Lau

10

1 reference

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24 January 2020

Yonghong Xiao

11

1 reference

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24 January 2020

Amanda L Christie

12

1 reference

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24 January 2020

Jon Aster

13

1 reference

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24 January 2020

Jeffrey Settleman

14

1 reference

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24 January 2020

Keiichi I Nakayama

18

1 reference

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24 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

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24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21368833%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

471

1 reference

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24 January 2020

issue

7336

1 reference

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24 January 2020

page(s)

104-109

1 reference

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https://scigraph.springernature.com/pub.10.1038/nature09732

24 January 2020

exact match

0 references

cites work

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Mcl-1 is a potential therapeutic target in multiple types of cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Oncogene addiction: setting the stage for molecularly targeted cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

GSK-3beta inhibition enhances sorafenib-induced apoptosis in melanoma cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The genomic landscapes of human breast and colorectal cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The ubiquitin-specific protease USP28 is required for MYC stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Involvement of the SCF complex in the control of Cdh1 degradation in S-phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

AP-1 as a regulator of cell life and death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

8 July 2018

A convoluted way to die.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076007

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

26 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09732

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE09732

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21368833%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21368833%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference