(Q39582682)

13 September 2017

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. (English)

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13 September 2017

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10

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13 September 2017

Elizabeth Helgason

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Daniel J. Anderson

object named as

Daniel J Anderson

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Mark L Chiu

object named as

Mark L Chiu

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author name string

Ingrid E Wertz

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13 September 2017

Saritha Kusam

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13 September 2017

Cynthia Lam

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13 September 2017

Toru Okamoto

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13 September 2017

Wendy Sandoval

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13 September 2017

James A Ernst

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13 September 2017

Mike Eby

9

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13 September 2017

Lisa D Belmont

11

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13 September 2017

Josh S Kaminker

12

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13 September 2017

Karen M O'Rourke

13

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13 September 2017

Kanan Pujara

14

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13 September 2017

Pawan Bir Kohli

15

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13 September 2017

Adam R Johnson

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13 September 2017

Jennie R Lill

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13 September 2017

Peter K Jackson

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13 September 2017

Wayne J Fairbrother

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13 September 2017

Somasekar Seshagiri

21

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13 September 2017

Mary J C Ludlam

22

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13 September 2017

Kevin G Leong

23

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13 September 2017

Erin C Dueber

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13 September 2017

Heather Maecker

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13 September 2017

David C S Huang

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13 September 2017

Vishva M Dixit

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13 September 2017

language of work or name

English

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publication date

1 March 2011

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13 September 2017

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13 September 2017

471

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13 September 2017

110-114

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13 September 2017

7336

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https://scigraph.springernature.com/pub.10.1038/nature09779

13 September 2017

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cites work

Recognition and processing of ubiquitin-protein conjugates by the proteasome

1 reference

12 December 2020

The reversibility of mitotic exit in vertebrate cells

1 reference

12 December 2020

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

1 reference

12 December 2020

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1 reference

12 December 2020

Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.

1 reference

12 December 2020

Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis

1 reference

12 December 2020

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

1 reference

12 December 2020

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

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12 December 2020

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

12 December 2020

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

12 December 2020

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

1 reference

12 December 2020

Multidrug resistance gene-1 (Pgp) expression in epithelial ovarian malignancies.

1 reference

12 December 2020

No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

1 reference

12 December 2020

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

12 December 2020

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

1 reference

12 December 2020

Targeted anti-mitotic therapies: can we improve on tubulin agents?

1 reference

12 December 2020

Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

1 reference

12 December 2020

RING domain E3 ubiquitin ligases

1 reference

12 December 2020

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

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12 December 2020

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE09779

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Dimensions Publication ID

13 September 2017

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