(Q35579558)

English

Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir

scientific article published on 19 September 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Evan D Kharasch

3

object named as

Evan D Kharasch

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Brian J Kirby

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Ann C Collier

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Vaishali Dixit

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Pankaj Desai

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dale Whittington

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Kenneth E Thummel

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Jashvant D Unadkat

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

19 September 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

39

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2329-2337

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Complex drug interactions of HIV protease inhibitors 1: inactivation, induction, and inhibition of cytochrome P450 3A by ritonavir or nelfinavir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodefic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

A review of low-dose ritonavir in protease inhibitor combination therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

27 July 2018

The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Dose-related reduction in bupropion plasma concentrations by ritonavir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich-cultured rat and human hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

A combined model for predicting CYP3A4 clinical net drug-drug interaction based on CYP3A4 inhibition, inactivation, and induction determined in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Stereoselective bupropion hydroxylation as an in vivo phenotypic probe for cytochrome P4502B6 (CYP2B6) activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Interaction between lopinavir/ritonavir and warfarin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Metabolism of the human immunodeficiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome P4503A4/3A5: mechanism-based inactivation of cytochrome P4503A by ritonavir.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226381

26 September 2018

Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alprazolam-ritonavir interaction: implications for product labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo modulation of CYP enzymes by quinidine and rifampin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paraxanthine metabolism in humans: determination of metabolic partial clearances and effects of allopurinol and cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ritonavir. Clinical pharmacokinetics and interactions with other anti-HIV agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro LC-MS cocktail assays to simultaneously determine human cytochrome P450 activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective analysis of bupropion and hydroxybupropion in human plasma and urine by LC/MS/MS

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/21930825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.111.038646

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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