(Q35589285)

9 August 2017

title

Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant-dependent lung carcinomas (English)

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9 August 2017

16

Kwok-Kin Wong

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9 August 2017

12

Achim A Jungbluth

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9 August 2017

14

Lloyd J Old

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9 August 2017

Danan Li

1

1 reference

9 August 2017

Hongbin Ji

2

1 reference

9 August 2017

Sara Zaghlul

3

1 reference

9 August 2017

Kate McNamara

4

1 reference

9 August 2017

Mei-Chih Liang

5

1 reference

9 August 2017

Takeshi Shimamura

6

1 reference

9 August 2017

Shigeto Kubo

7

1 reference

9 August 2017

Masaya Takahashi

8

1 reference

9 August 2017

Lucian R Chirieac

9

1 reference

9 August 2017

Robert F Padera

10

1 reference

9 August 2017

Andrew M Scott

11

1 reference

9 August 2017

Webster K Cavenee

13

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9 August 2017

George D Demetri

15

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9 August 2017

language of work or name

English

0 references

publication date

25 January 2007

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Journal of Clinical Investigation

9 August 2017

published in

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9 August 2017

volume

117

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9 August 2017

issue

2

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9 August 2017

page(s)

346-352

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describes a project that uses

9 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1770949/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

12 July 2018

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Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors

12 July 2018

1 reference

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Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations

12 July 2018

1 reference

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors

12 July 2018

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Targeting the epidermal growth factor receptor in colorectal cancer: advances and controversies

12 July 2018

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Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

12 July 2018

1 reference

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A review of the benefit-risk profile of gefitinib in Asian patients with advanced non-small-cell lung cancer

12 July 2018

1 reference

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Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours

12 July 2018

1 reference

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Overview of monoclonal antibodies and small molecules targeting the epidermal growth factor receptor pathway in colorectal cancer.

12 July 2018

1 reference

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Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

ERBB receptors and cancer: the complexity of targeted inhibitors

12 July 2018

1 reference

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Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

12 July 2018

Therapeutic antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

ErbB-targeted therapeutic approaches in human cancer

12 July 2018

1 reference

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A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor

12 July 2018

1 reference

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Targeted therapy in non-small-cell lung cancer.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

The EGF receptor family as targets for cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Three-dimensional magnetic resonance microscopy of pulmonary solitary tumors in transgenic mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

[Mutations in the epidermal growth factor receptor: structure and biological function in human tumors].

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770949

26 September 2018

Identifiers

DOI

10.1172/JCI30446

1 reference

9 August 2017

1 reference

9 August 2017

1 reference